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Compile Data Set for Download or QSAR

Found 52 hits Enz. Inhib. hit(s) with Target = 'Patatin-like phospholipase domain-containing protein 2'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Patatin-like phospholipase domain-containing protein 2


(Homo sapiens)
BDBM50185419
PNG
(CHEMBL3823931)
Show SMILES CN(C)C(=O)Nc1cccc(c1)-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C17H21N3O/c1-19(2)16-10-8-13(9-11-16)14-6-5-7-15(12-14)18-17(21)20(3)4/h5-12H,1-4H3,(H,18,21)
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n/an/a 700n/an/an/an/an/an/a



Universit£ de Moncton

Curated by ChEMBL


Assay Description
Inhibition of ATGL (unknown origin) overexpressed in Escherichia coli XL-1 cells using [9,10-3H(N)]triolein as substrate incubated for 60 mins by liq...


Eur J Med Chem 118: 290-8 (2016)

More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084691
PNG
(CHEMBL3427325)
Show SMILES Oc1ccc(\C=N\N2CCN(CC2)c2ccccc2)c(O)c1
Show InChI InChI=1S/C17H19N3O2/c21-16-7-6-14(17(22)12-16)13-18-20-10-8-19(9-11-20)15-4-2-1-3-5-15/h1-7,12-13,21-22H,8-11H2/b18-13+
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n/an/a 1.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084923
PNG
(CHEMBL3427360)
Show SMILES Oc1ccc(\C=N\N2CCC(CC2)c2ccccc2)c(O)c1
Show InChI InChI=1S/C18H20N2O2/c21-17-7-6-16(18(22)12-17)13-19-20-10-8-15(9-11-20)14-4-2-1-3-5-14/h1-7,12-13,15,21-22H,8-11H2/b19-13+
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n/an/a 4.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084690
PNG
(CHEMBL3427324)
Show SMILES Oc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C17H19N3O/c21-17-8-6-15(7-9-17)14-18-20-12-10-19(11-13-20)16-4-2-1-3-5-16/h1-9,14,21H,10-13H2/b18-14+
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n/an/a 5.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084917
PNG
(CHEMBL3427354)
Show SMILES Oc1ccc(\C=N\N2CCN(CC2)c2ccc(F)cc2)c(O)c1
Show InChI InChI=1S/C17H18FN3O2/c18-14-2-4-15(5-3-14)20-7-9-21(10-8-20)19-12-13-1-6-16(22)11-17(13)23/h1-6,11-12,22-23H,7-10H2/b19-12+
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n/an/a 5.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084842
PNG
(CHEMBL3427336)
Show SMILES N#Cc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C18H18N4/c19-14-16-6-8-17(9-7-16)15-20-22-12-10-21(11-13-22)18-4-2-1-3-5-18/h1-9,15H,10-13H2/b20-15+
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n/an/a 5.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084662
PNG
(CHEMBL3427321)
Show SMILES COc1cc(\C=N\N2CCN(CC2)c2ccccc2)ccc1O
Show InChI InChI=1S/C18H21N3O2/c1-23-18-13-15(7-8-17(18)22)14-19-21-11-9-20(10-12-21)16-5-3-2-4-6-16/h2-8,13-14,22H,9-12H2,1H3/b19-14+
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n/an/a 6.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084668
PNG
(CHEMBL3427322)
Show SMILES Oc1cccc(\C=N\N2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C17H19N3O/c21-17-8-4-5-15(13-17)14-18-20-11-9-19(10-12-20)16-6-2-1-3-7-16/h1-8,13-14,21H,9-12H2/b18-14+
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n/an/a 7.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084769
PNG
(CHEMBL3427330)
Show SMILES Fc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1F
Show InChI InChI=1S/C17H17F2N3/c18-16-7-6-14(12-17(16)19)13-20-22-10-8-21(9-11-22)15-4-2-1-3-5-15/h1-7,12-13H,8-11H2/b20-13+
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n/an/a 7.50E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084672
PNG
(CHEMBL3427323)
Show SMILES Oc1ccccc1\C=N\N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C17H19N3O/c21-17-9-5-4-6-15(17)14-18-20-12-10-19(11-13-20)16-7-2-1-3-8-16/h1-9,14,21H,10-13H2/b18-14+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084656
PNG
(CHEMBL3427320)
Show SMILES COc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1O
Show InChI InChI=1S/C18H21N3O2/c1-23-18-8-7-15(13-17(18)22)14-19-21-11-9-20(10-12-21)16-5-3-2-4-6-16/h2-8,13-14,22H,9-12H2,1H3/b19-14+
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n/an/a 8.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084654
PNG
(CHEMBL3427319)
Show SMILES COc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1OC
Show InChI InChI=1S/C19H23N3O2/c1-23-18-9-8-16(14-19(18)24-2)15-20-22-12-10-21(11-13-22)17-6-4-3-5-7-17/h3-9,14-15H,10-13H2,1-2H3/b20-15+
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n/an/a 1.00E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084930
PNG
(CHEMBL3427366)
Show SMILES Fc1ccc(OC(=O)N2CCN(CC2)c2ccccc2)cc1F
Show InChI InChI=1S/C17H16F2N2O2/c18-15-7-6-14(12-16(15)19)23-17(22)21-10-8-20(9-11-21)13-4-2-1-3-5-13/h1-7,12H,8-11H2
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n/an/a 1.10E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084653
PNG
(CHEMBL2094513 | DNDI1417188)
Show SMILES Oc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1O
Show InChI InChI=1S/C17H19N3O2/c21-16-7-6-14(12-17(16)22)13-18-20-10-8-19(9-11-20)15-4-2-1-3-5-15/h1-7,12-13,21-22H,8-11H2/b18-13+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084932
PNG
(CHEMBL3427367)
Show SMILES CCOC(=O)c1nn(cc1O)-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C14H17N3O3/c1-4-20-14(19)13-12(18)9-17(15-13)11-7-5-10(6-8-11)16(2)3/h5-9,18H,4H2,1-3H3
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n/an/a 1.20E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084841
PNG
(CHEMBL3427335)
Show SMILES N#Cc1ccccc1\C=N\N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C18H18N4/c19-14-16-6-4-5-7-17(16)15-20-22-12-10-21(11-13-22)18-8-2-1-3-9-18/h1-9,15H,10-13H2/b20-15+
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n/an/a 1.20E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084887
PNG
(CHEMBL3427346)
Show SMILES C1CCC(\C=N\N2CCN(CC2)c2ccccc2)=CC1
Show InChI InChI=1S/C17H23N3/c1-3-7-16(8-4-1)15-18-20-13-11-19(12-14-20)17-9-5-2-6-10-17/h2,5-7,9-10,15H,1,3-4,8,11-14H2/b18-15+
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n/an/a 1.30E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084901
PNG
(CHEMBL3427349)
Show SMILES C1CN(CCN1\N=C\c1ccncc1)c1ccccc1
Show InChI InChI=1S/C16H18N4/c1-2-4-16(5-3-1)19-10-12-20(13-11-19)18-14-15-6-8-17-9-7-15/h1-9,14H,10-13H2/b18-14+
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n/an/a 1.40E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084840
PNG
(CHEMBL3427334)
Show SMILES Brc1ccccc1\C=N\N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C17H18BrN3/c18-17-9-5-4-6-15(17)14-19-21-12-10-20(11-13-21)16-7-2-1-3-8-16/h1-9,14H,10-13H2/b19-14+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084838
PNG
(CHEMBL3427333)
Show SMILES [O-][N+](=O)c1ccccc1\C=N\N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C17H18N4O2/c22-21(23)17-9-5-4-6-15(17)14-18-20-12-10-19(11-13-20)16-7-2-1-3-8-16/h1-9,14H,10-13H2/b18-14+
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n/an/a 1.80E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084845
PNG
(CHEMBL3427338)
Show SMILES CC(=O)Nc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C19H22N4O/c1-16(24)21-18-9-7-17(8-10-18)15-20-23-13-11-22(12-14-23)19-5-3-2-4-6-19/h2-10,15H,11-14H2,1H3,(H,21,24)/b20-15+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084847
PNG
(CHEMBL3427339)
Show SMILES CN(CCO)c1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C20H26N4O/c1-22(15-16-25)19-9-7-18(8-10-19)17-21-24-13-11-23(12-14-24)20-5-3-2-4-6-20/h2-10,17,25H,11-16H2,1H3/b21-17+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084850
PNG
(CHEMBL3427340)
Show SMILES C1Oc2ccc(\C=N\N3CCN(CC3)c3ccccc3)cc2O1
Show InChI InChI=1S/C18H19N3O2/c1-2-4-16(5-3-1)20-8-10-21(11-9-20)19-13-15-6-7-17-18(12-15)23-14-22-17/h1-7,12-13H,8-11,14H2/b19-13+
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n/an/a>2.00E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084882
PNG
(CHEMBL3427341)
Show SMILES C1COc2cc(\C=N\N3CCN(CC3)c3ccccc3)ccc2O1
Show InChI InChI=1S/C19H21N3O2/c1-2-4-17(5-3-1)21-8-10-22(11-9-21)20-15-16-6-7-18-19(14-16)24-13-12-23-18/h1-7,14-15H,8-13H2/b20-15+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084883
PNG
(CHEMBL3427342)
Show SMILES O=c1[nH]c2ccc(\C=N\N3CCN(CC3)c3ccccc3)cc2[nH]1
Show InChI InChI=1S/C18H19N5O/c24-18-20-16-7-6-14(12-17(16)21-18)13-19-23-10-8-22(9-11-23)15-4-2-1-3-5-15/h1-7,12-13H,8-11H2,(H2,20,21,24)/b19-13+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084884
PNG
(CHEMBL3427343)
Show SMILES CCCC\C=N\N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C15H23N3/c1-2-3-7-10-16-18-13-11-17(12-14-18)15-8-5-4-6-9-15/h4-6,8-10H,2-3,7,11-14H2,1H3/b16-10+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084885
PNG
(CHEMBL3427344)
Show SMILES CCC\C=C\C=N\N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C16H23N3/c1-2-3-4-8-11-17-19-14-12-18(13-15-19)16-9-6-5-7-10-16/h4-11H,2-3,12-15H2,1H3/b8-4+,17-11+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084886
PNG
(CHEMBL3427345)
Show SMILES C1CCC(CC1)\C=N\N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C17H25N3/c1-3-7-16(8-4-1)15-18-20-13-11-19(12-14-20)17-9-5-2-6-10-17/h2,5-6,9-10,15-16H,1,3-4,7-8,11-14H2/b18-15+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084888
PNG
(CHEMBL3427347)
Show SMILES C1CN(CCN1\N=C\c1ccccn1)c1ccccc1
Show InChI InChI=1S/C16H18N4/c1-2-7-16(8-3-1)19-10-12-20(13-11-19)18-14-15-6-4-5-9-17-15/h1-9,14H,10-13H2/b18-14+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084889
PNG
(CHEMBL3427348)
Show SMILES C1CN(CCN1\N=C\c1cccnc1)c1ccccc1
Show InChI InChI=1S/C16H18N4/c1-2-6-16(7-3-1)19-9-11-20(12-10-19)18-14-15-5-4-8-17-13-15/h1-8,13-14H,9-12H2/b18-14+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084902
PNG
(CHEMBL3427350)
Show SMILES C1CN(CCN1\N=C\c1ccc2ccccc2c1)c1ccccc1
Show InChI InChI=1S/C21H21N3/c1-2-8-21(9-3-1)23-12-14-24(15-13-23)22-17-18-10-11-19-6-4-5-7-20(19)16-18/h1-11,16-17H,12-15H2/b22-17+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084914
PNG
(CHEMBL3427351)
Show SMILES C1CN(CCN1\N=C\c1ccc2ccccc2n1)c1ccccc1
Show InChI InChI=1S/C20H20N4/c1-2-7-19(8-3-1)23-12-14-24(15-13-23)21-16-18-11-10-17-6-4-5-9-20(17)22-18/h1-11,16H,12-15H2/b21-16+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084915
PNG
(CHEMBL3427352)
Show SMILES C1CN(CCN1\N=C\c1cccc2ccccc12)c1ccccc1
Show InChI InChI=1S/C21H21N3/c1-2-10-20(11-3-1)23-13-15-24(16-14-23)22-17-19-9-6-8-18-7-4-5-12-21(18)19/h1-12,17H,13-16H2/b22-17+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084916
PNG
(CHEMBL3427353)
Show SMILES Oc1ccc(\C=N\N2CCN(CC2)c2ccncc2)c(O)c1
Show InChI InChI=1S/C16H18N4O2/c21-15-2-1-13(16(22)11-15)12-18-20-9-7-19(8-10-20)14-3-5-17-6-4-14/h1-6,11-12,21-22H,7-10H2/b18-12+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084767
PNG
(CHEMBL3427329)
Show SMILES COc1cc(\C=N\N2CCN(CC2)c2ccccc2)cc(OC)c1OC
Show InChI InChI=1S/C20H25N3O3/c1-24-18-13-16(14-19(25-2)20(18)26-3)15-21-23-11-9-22(10-12-23)17-7-5-4-6-8-17/h4-8,13-15H,9-12H2,1-3H3/b21-15+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084918
PNG
(CHEMBL3427355)
Show SMILES Cc1cccc(c1)N1CCN(CC1)\N=C\c1ccc(O)cc1O
Show InChI InChI=1S/C18H21N3O2/c1-14-3-2-4-16(11-14)20-7-9-21(10-8-20)19-13-15-5-6-17(22)12-18(15)23/h2-6,11-13,22-23H,7-10H2,1H3/b19-13+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084919
PNG
(CHEMBL3427356)
Show SMILES Oc1ccc(\C=N\N2CCN(Cc3ccccc3)CC2)c(O)c1
Show InChI InChI=1S/C18H21N3O2/c22-17-7-6-16(18(23)12-17)13-19-21-10-8-20(9-11-21)14-15-4-2-1-3-5-15/h1-7,12-13,22-23H,8-11,14H2/b19-13+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084920
PNG
(CHEMBL3427357)
Show SMILES Oc1ccc(\C=N\N2CCN(CCc3ccccc3)CC2)c(O)c1
Show InChI InChI=1S/C19H23N3O2/c23-18-7-6-17(19(24)14-18)15-20-22-12-10-21(11-13-22)9-8-16-4-2-1-3-5-16/h1-7,14-15,23-24H,8-13H2/b20-15+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084921
PNG
(CHEMBL3427358)
Show SMILES Oc1ccc(\C=N\N2CCN(CC2)C2CCCCC2)c(O)c1
Show InChI InChI=1S/C17H25N3O2/c21-16-7-6-14(17(22)12-16)13-18-20-10-8-19(9-11-20)15-4-2-1-3-5-15/h6-7,12-13,15,21-22H,1-5,8-11H2/b18-13+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084922
PNG
(CHEMBL3427359)
Show SMILES Oc1ccc(\C=N\N2CCN(CC2)C2CCCC2)c(O)c1
Show InChI InChI=1S/C16H23N3O2/c20-15-6-5-13(16(21)11-15)12-17-19-9-7-18(8-10-19)14-3-1-2-4-14/h5-6,11-12,14,20-21H,1-4,7-10H2/b17-12+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084766
PNG
(CHEMBL3427328)
Show SMILES COc1cc(OC)c(\C=N\N2CCN(CC2)c2ccccc2)cc1OC
Show InChI InChI=1S/C20H25N3O3/c1-24-18-14-20(26-3)19(25-2)13-16(18)15-21-23-11-9-22(10-12-23)17-7-5-4-6-8-17/h4-8,13-15H,9-12H2,1-3H3/b21-15+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084924
PNG
(CHEMBL3427361)
Show SMILES Oc1ccc(\C=N\N2CCC(Cc3ccccc3)CC2)c(O)c1
Show InChI InChI=1S/C19H22N2O2/c22-18-7-6-17(19(23)13-18)14-20-21-10-8-16(9-11-21)12-15-4-2-1-3-5-15/h1-7,13-14,16,22-23H,8-12H2/b20-14+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084925
PNG
(CHEMBL3427362)
Show SMILES Oc1ccc(\C=N\N2CCCN(CC2)c2ccccc2)c(O)c1
Show InChI InChI=1S/C18H21N3O2/c22-17-8-7-15(18(23)13-17)14-19-21-10-4-9-20(11-12-21)16-5-2-1-3-6-16/h1-3,5-8,13-14,22-23H,4,9-12H2/b19-14+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084926
PNG
(CHEMBL3427363)
Show SMILES Oc1ccc(CN2CCN(CC2)c2ccccc2)cc1O
Show InChI InChI=1S/C17H20N2O2/c20-16-7-6-14(12-17(16)21)13-18-8-10-19(11-9-18)15-4-2-1-3-5-15/h1-7,12,20-21H,8-11,13H2
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084927
PNG
(CHEMBL3427364)
Show SMILES COc1ccc(cc1OC)C(=O)NN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C19H23N3O3/c1-24-17-9-8-15(14-18(17)25-2)19(23)20-22-12-10-21(11-13-22)16-6-4-3-5-7-16/h3-9,14H,10-13H2,1-2H3,(H,20,23)
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084928
PNG
(CHEMBL3427365)
Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2)cc1OC
Show InChI InChI=1S/C19H23N3O3/c1-24-17-9-8-15(14-18(17)25-2)20-19(23)22-12-10-21(11-13-22)16-6-4-3-5-7-16/h3-9,14H,10-13H2,1-2H3,(H,20,23)
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084765
PNG
(CHEMBL3427327)
Show SMILES C1CN(CCN1\N=C\c1cccc(Oc2ccccc2)c1)c1ccccc1
Show InChI InChI=1S/C23H23N3O/c1-3-9-21(10-4-1)25-14-16-26(17-15-25)24-19-20-8-7-13-23(18-20)27-22-11-5-2-6-12-22/h1-13,18-19H,14-17H2/b24-19+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084844
PNG
(CHEMBL3427337)
Show SMILES CN(C)c1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C19H24N4/c1-21(2)18-10-8-17(9-11-18)16-20-23-14-12-22(13-15-23)19-6-4-3-5-7-19/h3-11,16H,12-15H2,1-2H3/b20-16+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084843
PNG
(CHEMBL3211065)
Show SMILES Cc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C18H21N3/c1-16-7-9-17(10-8-16)15-19-21-13-11-20(12-14-21)18-5-3-2-4-6-18/h2-10,15H,11-14H2,1H3/b19-15+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084770
PNG
(CHEMBL3427331)
Show SMILES Clc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1Cl
Show InChI InChI=1S/C17H17Cl2N3/c18-16-7-6-14(12-17(16)19)13-20-22-10-8-21(9-11-22)15-4-2-1-3-5-15/h1-7,12-13H,8-11H2/b20-13+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
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