Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM18134![]() (({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEBI KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85447![]() (Epoxy analogue, I(a)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | 7.00E+3 | -30.6 | 5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367328![]() (CHEMBL1791415) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable... | J Med Chem 29: 1030-8 (1986) Article DOI: 10.1021/jm00156a022 BindingDB Entry DOI: 10.7270/Q2CF9QN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367329![]() (CHEMBL1791416) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable... | J Med Chem 29: 1030-8 (1986) Article DOI: 10.1021/jm00156a022 BindingDB Entry DOI: 10.7270/Q2CF9QN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50452293![]() (CHEMBL2092766) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable... | J Med Chem 29: 1030-8 (1986) Article DOI: 10.1021/jm00156a022 BindingDB Entry DOI: 10.7270/Q2CF9QN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367301![]() (CHEMBL1791432) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as Ki | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85448![]() (Epoxy analogue, I(b)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | KEGG PC cid PC sid UniChem Similars | Article PubMed | 6.10E+4 | -25.0 | 1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367042![]() (CHEMBL606221) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85450![]() (Epithioamino acid analogue, II(a)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 1.00E+5 | -23.7 | 1.40E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85449![]() (Epoxy analogue, I(c)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.05E+5 | -23.6 | 1.10E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85451![]() (Epithioamino acid analogue, II(b)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 1.40E+5 | -22.9 | 3.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM85452![]() (Epithioamino acid analogue, II(c)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 1.40E+5 | -22.9 | 4.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Laboratoire de chimie bioorganique | Assay Description AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi... | J Enzym Inhib 13: 361-7 (1998) Article DOI: 10.3109/14756369809021481 BindingDB Entry DOI: 10.7270/Q2668BQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50026197![]() (Adenosine 5'-triphosphate derivative | CHEMBL31428...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as Ki | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367331![]() (CHEMBL1791417) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable... | J Med Chem 29: 1030-8 (1986) Article DOI: 10.1021/jm00156a022 BindingDB Entry DOI: 10.7270/Q2CF9QN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50026193![]() (Adenosine 5'-triphosphate derivative | CHEMBL31428...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as Ki | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367329![]() (CHEMBL1791416) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable... | J Med Chem 29: 1030-8 (1986) Article DOI: 10.1021/jm00156a022 BindingDB Entry DOI: 10.7270/Q2CF9QN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367305![]() (CHEMBL1791430) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as Ki | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50452293![]() (CHEMBL2092766) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable... | J Med Chem 29: 1030-8 (1986) Article DOI: 10.1021/jm00156a022 BindingDB Entry DOI: 10.7270/Q2CF9QN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367307![]() (CHEMBL1791431) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as Ki | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50118221![]() (9H-purine derivative | CHEMBL132722 | DIPHOSPHOMET...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Similars | Article PubMed | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367300![]() (CHEMBL610977) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as Ki | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367303![]() (CHEMBL1791433) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 4.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II, activity expressed as Ki | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50025158![]() (2-Amino-3-methyl-4-methylsulfanyl-butyric acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibitory activity against Methionine adenosyltransferase II | J Med Chem 29: 1743-8 (1986) Article DOI: 10.1021/jm00159a030 BindingDB Entry DOI: 10.7270/Q24748V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367306![]() (CHEMBL608929) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 5.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50367304![]() (CHEMBL610404) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 5.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50118232![]() (2-MeSATP | ATP, 2-meS | CHEMBL336208) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 6.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II | J Med Chem 29: 318-22 (1986) Article DOI: 10.1021/jm00153a003 BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50025157![]() (2-Amino-2-methyl-4-methylsulfanyl-pentanoic acid |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibitory activity against M-2 Methionine adenosyltransferase II | J Med Chem 29: 1743-8 (1986) Article DOI: 10.1021/jm00159a030 BindingDB Entry DOI: 10.7270/Q24748V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM50025156![]() (2-Amino-4-methylsulfanyl-pentanoic acid | CHEMBL45...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibitory activity against Methionine adenosyltransferase II | J Med Chem 29: 1743-8 (1986) Article DOI: 10.1021/jm00159a030 BindingDB Entry DOI: 10.7270/Q24748V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559541![]() (CHEMBL4746939) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s... | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559542![]() (CHEMBL4746079) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s... | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559543![]() (CHEMBL4754086) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s... | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559544![]() (CHEMBL4751206) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s... | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559545![]() (CHEMBL4762089) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s... | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559546![]() (CHEMBL4760483) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s... | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559547![]() (CHEMBL4754303) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s... | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559548![]() (CHEMBL4741054) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s... | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559549![]() (CHEMBL4786665) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s... | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559549![]() (CHEMBL4786665) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysis | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559548![]() (CHEMBL4741054) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysis | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559547![]() (CHEMBL4754303) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysis | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559546![]() (CHEMBL4760483) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysis | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559544![]() (CHEMBL4751206) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysis | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559543![]() (CHEMBL4754086) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysis | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559542![]() (CHEMBL4746079) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysis | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559541![]() (CHEMBL4746939) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysis | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559540![]() (CHEMBL4750527) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysis | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM50559540![]() (CHEMBL4750527) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Usona Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s... | ACS Med Chem Lett 12: 180-181 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM508347![]() (1-(2-chlorophenyl)-7-(1,1- difluoroethyl)-4- (meth...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <200 | n/a | n/a | n/a | n/a | n/a | n/a |
IDEAYA BIOSCIENCES, INC. US Patent | Assay Description MAT2A enzyme is incubated with a test compound in DMSO or DMSO and its substrates (L-methionine and ATP) in a microtiter plate. The enzymatic reactio... | US Patent US11046691 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM508348![]() (1-(3-chloropyridin-2-yl)-7-ethyl-4- (methylamino)q...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <200 | n/a | n/a | n/a | n/a | n/a | n/a |
IDEAYA BIOSCIENCES, INC. US Patent | Assay Description MAT2A enzyme is incubated with a test compound in DMSO or DMSO and its substrates (L-methionine and ATP) in a microtiter plate. The enzymatic reactio... | US Patent US11046691 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Human) | BDBM508349![]() (4-amino-1-(3-chloropyridin-2-yl)-7- (1,1-difluoroe...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <200 | n/a | n/a | n/a | n/a | n/a | n/a |
IDEAYA BIOSCIENCES, INC. US Patent | Assay Description MAT2A enzyme is incubated with a test compound in DMSO or DMSO and its substrates (L-methionine and ATP) in a microtiter plate. The enzymatic reactio... | US Patent US11046691 (2021) | |||||||||||
More data for this Ligand-Target Pair |
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