Compile Data Set for Download or QSAR

Found 210 hits Enz. Inhib. hit(s) with Target = 'Serotonin 1d (5-HT1d) receptor'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1D (5HT1D) (Mus musculus (Mouse))	BDBM86708 (CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, binding (Experi...				J Med Chem 42: 1576-86 (1999) Article DOI: 10.1021/jm980456f BindingDB Entry DOI: 10.7270/Q23R0S2J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (5HT1D) (Mus musculus (Mouse))	BDBM50076428 (4-Fluoro-cyclohexanecarboxylic acid {2-[4-(2-metho...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCC(F)CC2)c2ccccn2)CC1 Show InChI InChI=1S/C25H33FN4O2/c1-32-23-7-3-2-6-22(23)29-17-14-28(15-18-29)16-19-30(24-8-4-5-13-27-24)25(31)20-9-11-21(26)12-10-20/h2-8,13,20-21H,9-12,14-19H2,1H3	Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, binding				J Med Chem 42: 1576-86 (1999) Article DOI: 10.1021/jm980456f BindingDB Entry DOI: 10.7270/Q23R0S2J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (5HT1D) (Mus musculus (Mouse))	BDBM86708 (CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]GTP-gamma-S, binding (Experi...				J Med Chem 42: 1576-86 (1999) Article DOI: 10.1021/jm980456f BindingDB Entry DOI: 10.7270/Q23R0S2J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (5HT1D) (Mus musculus (Mouse))	BDBM50076429 (4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)c2ccc(F)c(C)c2)c2ccccn2)CC1 Show InChI InChI=1S/C26H29FN4O2/c1-20-19-21(10-11-22(20)27)26(32)31(25-9-5-6-12-28-25)18-15-29-13-16-30(17-14-29)23-7-3-4-8-24(23)33-2/h3-12,19H,13-18H2,1-2H3	Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, binding (Experi...				J Med Chem 42: 1576-86 (1999) Article DOI: 10.1021/jm980456f BindingDB Entry DOI: 10.7270/Q23R0S2J
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM79215 (CHEMBL15928 | GR 127935 | GR 127935 hydrochloride ...) Show SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2ccc(cc2C)-c2noc(C)n2)cc1N1CCN(C)CC1 Show InChI InChI=1S/C29H31N5O3/c1-19-17-23(28-30-20(2)37-32-28)9-11-25(19)21-5-7-22(8-6-21)29(35)31-24-10-12-27(36-4)26(18-24)34-15-13-33(3)14-16-34/h5-12,17-18H,13-16H2,1-4H3,(H,31,35)	UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Ltd. Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1D receptor in guinea-pig striatum in presence of BMY-7378 and mesulergine				J Med Chem 37: 2253-7 (1994) BindingDB Entry DOI: 10.7270/Q29889QB
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM50469879 (CHEMBL72088) Show SMILES COc1ccc(cc1N1CCN(C)CC1)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H26N4O2/c1-27-13-15-28(16-14-27)22-17-20(5-8-23(22)30-2)24(29)26-21-6-3-18(4-7-21)19-9-11-25-12-10-19/h3-12,17H,13-16H2,1-2H3,(H,26,29)	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Ltd. Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1D receptor in guinea-pig striatum in presence of BMY-7378 and mesulergine				J Med Chem 37: 2253-7 (1994) BindingDB Entry DOI: 10.7270/Q29889QB
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM50469882 (CHEMBL73446) Show SMILES COCCOC(=O)c1ccc(c(C)c1)-c1ccc(NC(=O)c2ccc(OC)c(CCCN(C)C)c2)cc1 Show InChI InChI=1S/C30H36N2O5/c1-21-19-25(30(34)37-18-17-35-4)10-14-27(21)22-8-12-26(13-9-22)31-29(33)24-11-15-28(36-5)23(20-24)7-6-16-32(2)3/h8-15,19-20H,6-7,16-18H2,1-5H3,(H,31,33)	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Ltd. Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1D receptor in guinea-pig striatum in presence of BMY-7378 and mesulergine				J Med Chem 37: 2253-7 (1994) BindingDB Entry DOI: 10.7270/Q29889QB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (5HT1D) (Mus musculus (Mouse))	BDBM50076429 (4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)c2ccc(F)c(C)c2)c2ccccn2)CC1 Show InChI InChI=1S/C26H29FN4O2/c1-20-19-21(10-11-22(20)27)26(32)31(25-9-5-6-12-28-25)18-15-29-13-16-30(17-14-29)23-7-3-4-8-24(23)33-2/h3-12,19H,13-18H2,1-2H3	Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]GTP-gamma-S, binding				J Med Chem 42: 1576-86 (1999) Article DOI: 10.1021/jm980456f BindingDB Entry DOI: 10.7270/Q23R0S2J
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM50469875 (CHEMBL72981) Show SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2ccncc2)cc1N1CCN(C)CC1 Show InChI InChI=1S/C24H26N4O2/c1-27-13-15-28(16-14-27)22-17-21(7-8-23(22)30-2)26-24(29)20-5-3-18(4-6-20)19-9-11-25-12-10-19/h3-12,17H,13-16H2,1-2H3,(H,26,29)	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Ltd. Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1D receptor in guinea-pig striatum in presence of BMY-7378 and mesulergine				J Med Chem 37: 2253-7 (1994) BindingDB Entry DOI: 10.7270/Q29889QB
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM50469881 (CHEMBL311150) Show SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2ccc(cc2C)C(=O)N(C)C)cc1N1CCN(C)CC1 Show InChI InChI=1S/C29H34N4O3/c1-20-18-23(29(35)31(2)3)10-12-25(20)21-6-8-22(9-7-21)28(34)30-24-11-13-27(36-5)26(19-24)33-16-14-32(4)15-17-33/h6-13,18-19H,14-17H2,1-5H3,(H,30,34)	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Ltd. Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1D receptor in guinea-pig striatum in presence of BMY-7378 and mesulergine				J Med Chem 37: 2253-7 (1994) BindingDB Entry DOI: 10.7270/Q29889QB
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM50469876 (CHEMBL306384) Show SMILES COc1ccc(cc1N1CCN(C)CC1)C(=O)Nc1ccc(cc1)-c1ccc(cc1C)-c1noc(C)n1 Show InChI InChI=1S/C29H31N5O3/c1-19-17-22(28-30-20(2)37-32-28)7-11-25(19)21-5-9-24(10-6-21)31-29(35)23-8-12-27(36-4)26(18-23)34-15-13-33(3)14-16-34/h5-12,17-18H,13-16H2,1-4H3,(H,31,35)	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Ltd. Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1D receptor in guinea-pig striatum in presence of BMY-7378 and mesulergine				J Med Chem 37: 2253-7 (1994) BindingDB Entry DOI: 10.7270/Q29889QB
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM50469878 (CHEMBL72700) Show SMILES COc1ccc(cc1CCCN(C)C)C(=O)Nc1ccc(cc1)-c1ccc(C=O)cc1C Show InChI InChI=1S/C27H30N2O3/c1-19-16-20(18-30)7-13-25(19)21-8-11-24(12-9-21)28-27(31)23-10-14-26(32-4)22(17-23)6-5-15-29(2)3/h7-14,16-18H,5-6,15H2,1-4H3,(H,28,31)	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Ltd. Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1D receptor in guinea-pig striatum in presence of BMY-7378 and mesulergine				J Med Chem 37: 2253-7 (1994) BindingDB Entry DOI: 10.7270/Q29889QB
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM50060518 (3-(3-Dimethylamino-propyl)-4-methoxy-N-(4-pyridin-...) Show SMILES COc1ccc(cc1CCCN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H27N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h6-15,17H,4-5,16H2,1-3H3,(H,26,28)	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Ltd. Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1D receptor in guinea-pig striatum in presence of BMY-7378 and mesulergine				J Med Chem 37: 2253-7 (1994) BindingDB Entry DOI: 10.7270/Q29889QB
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM50469877 (CHEMBL72092) Show SMILES COc1ccc(cc1CCCN(C)C)C(=O)Nc1ccc(cc1)-c1ccc(cc1C)C(O)=O Show InChI InChI=1S/C27H30N2O4/c1-18-16-22(27(31)32)9-13-24(18)19-7-11-23(12-8-19)28-26(30)21-10-14-25(33-4)20(17-21)6-5-15-29(2)3/h7-14,16-17H,5-6,15H2,1-4H3,(H,28,30)(H,31,32)	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Ltd. Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1D receptor in guinea-pig striatum in presence of BMY-7378 and mesulergine				J Med Chem 37: 2253-7 (1994) BindingDB Entry DOI: 10.7270/Q29889QB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (5HT1D) (Mus musculus (Mouse))	BDBM186927 (US9079895, 19s) Show SMILES C(CN1CCO[C@H](COc2ccccc2)C1)N1CCc2ccccc12 Show InChI InChI=1S/C21H26N2O2/c1-2-7-19(8-3-1)25-17-20-16-22(14-15-24-20)12-13-23-11-10-18-6-4-5-9-21(18)23/h1-9,20H,10-17H2/t20-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	US Patent	590	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Dundee US Patent					Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...				US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM50060417 (5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...) Show SMILES Cn1ccc2cc3N(CCc3cc12)C(=O)Nc1cccnc1 Show InChI InChI=1S/C17H16N4O/c1-20-7-4-12-10-16-13(9-15(12)20)5-8-21(16)17(22)19-14-3-2-6-18-11-14/h2-4,6-7,9-11H,5,8H2,1H3,(H,19,22)	UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by PDSP Ki Database									Br J Pharmacol 117: 427-434 (1996) Article DOI: 10.1111/j.1476-5381.1996.tb15208.x BindingDB Entry DOI: 10.7270/Q27W69Q5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (5HT1D) (Mus musculus (Mouse))	BDBM186935 (US9079895, 23s) Show SMILES Clc1cccc(OC[C@@H]2CN(CCN3CCc4ccccc34)CCO2)c1 Show InChI InChI=1S/C21H25ClN2O2/c22-18-5-3-6-19(14-18)26-16-20-15-23(12-13-25-20)10-11-24-9-8-17-4-1-2-7-21(17)24/h1-7,14,20H,8-13,15-16H2/t20-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	US Patent	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Dundee US Patent					Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...				US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (5HT1D) (Mus musculus (Mouse))	BDBM186937 (US9079895, 25s) Show SMILES COc1cccc(OC[C@@H]2CN(CCN3CCc4ccccc34)CCO2)c1 Show InChI InChI=1S/C22H28N2O3/c1-25-19-6-4-7-20(15-19)27-17-21-16-23(13-14-26-21)11-12-24-10-9-18-5-2-3-8-22(18)24/h2-8,15,21H,9-14,16-17H2,1H3/t21-/m0/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	US Patent	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
University of Dundee US Patent					Assay Description The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...				US Patent US9079895 (2015) BindingDB Entry DOI: 10.7270/Q2D7996K
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50129952 (2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...) Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 Show InChI InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H	UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Binding affinity (in vitro) against 5-hydroxytryptamine 1D receptor alpha using radio-ligand binding assay				Bioorg Med Chem Lett 13: 2281-4 (2003) Article DOI: 10.1016/s0960-894x(03)00434-7 BindingDB Entry DOI: 10.7270/Q2V987F7
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50056947 (CHEMBL354210 | N-{2-[4-(1,2,3,4-Tetrahydro-naphtha...) Show SMILES O=C(NCCN1CCN(CC1)C1CCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c27-23(20-8-2-1-3-9-20)24-13-14-25-15-17-26(18-16-25)22-12-6-10-19-7-4-5-11-21(19)22/h1-5,7-9,11,22H,6,10,12-18H2,(H,24,27)	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor using [3H]5-HT in pig striatum + frontalCortex				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50056944 (4-Fluoro-N-{2-[4-(1,2,3,4-tetrahydro-naphthalen-1-...) Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)C1CCCc2ccccc12 Show InChI InChI=1S/C23H28FN3O/c24-20-10-8-19(9-11-20)23(28)25-12-13-26-14-16-27(17-15-26)22-7-3-5-18-4-1-2-6-21(18)22/h1-2,4,6,8-11,22H,3,5,7,12-17H2,(H,25,28)	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cooperation Pharmaceutique Fran�aise Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor using [3H]5-HT in pig striatum + frontalCortex				J Med Chem 40: 952-60 (1997) Article DOI: 10.1021/jm950759z BindingDB Entry DOI: 10.7270/Q2HT2Q00
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM82505 (CAS_121881 | NSC_121881 | SB204070) Show SMILES CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3OCCOc23)CC1 Show InChI InChI=1S/C19H27ClN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3	UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by PDSP Ki Database									Br J Pharmacol 112: 789-94 (1994) Article DOI: 10.1111/j.1476-5381.1994.tb13148.x BindingDB Entry DOI: 10.7270/Q2N0151D
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM82272 (SB 200646 | SB200646a) Show SMILES Cn1ccc2cc(NC(=O)Nc3cccnc3)ccc12 Show InChI InChI=1S/C15H14N4O/c1-19-8-6-11-9-12(4-5-14(11)19)17-15(20)18-13-3-2-7-16-10-13/h2-10H,1H3,(H2,17,18,20)	UniProtKB/SwissProt GoogleScholar	Purchase KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by PDSP Ki Database									Behav Brain Res 73: 149-52 (1996) Article DOI: 10.1016/0166-4328(96)00087-3 BindingDB Entry DOI: 10.7270/Q2RX99ND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (5HT1D) (Mus musculus (Mouse))	BDBM79215 (CHEMBL15928 | GR 127935 | GR 127935 hydrochloride ...) Show SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2ccc(cc2C)-c2noc(C)n2)cc1N1CCN(C)CC1 Show InChI InChI=1S/C29H31N5O3/c1-19-17-23(28-30-20(2)37-32-28)9-11-25(19)21-5-7-22(8-6-21)29(35)31-24-10-12-27(36-4)26(18-24)34-15-13-33(3)14-16-34/h5-12,17-18H,13-16H2,1-4H3,(H,31,35)	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Similars	PubMed	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Ltd. Curated by ChEMBL					Assay Description Tested for 5-hydroxytryptamine receptor uptake				J Med Chem 37: 2253-7 (1994) BindingDB Entry DOI: 10.7270/Q29889QB
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406785 (CHEMBL39435) Show SMILES CNS(=O)(=O)c1ccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)cc1 Show InChI InChI=1S/C20H21N5O3S/c1-22-29(26,27)16-5-2-13(3-6-16)10-19-24-20(28-25-19)14-4-7-18-17(11-14)15(8-9-21)12-23-18/h2-7,11-12,22-23H,8-10,21H2,1H3	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.251	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406771 (L-694247) Show SMILES CS(=O)(=O)Nc1ccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)cc1 Show InChI InChI=1S/C20H21N5O3S/c1-29(26,27)25-16-5-2-13(3-6-16)10-19-23-20(28-24-19)14-4-7-18-17(11-14)15(8-9-21)12-22-18/h2-7,11-12,22,25H,8-10,21H2,1H3	UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.316	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding activity against 5-hydroxytryptamine 1D receptor from pig caudate membrane using [3H]5-HT as radioligand				J Med Chem 38: 1799-810 (1995) Article DOI: 10.1021/jm00010a025 BindingDB Entry DOI: 10.7270/Q20V8DZS
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406771 (L-694247) Show SMILES CS(=O)(=O)Nc1ccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)cc1 Show InChI InChI=1S/C20H21N5O3S/c1-29(26,27)25-16-5-2-13(3-6-16)10-19-23-20(28-24-19)14-4-7-18-17(11-14)15(8-9-21)12-22-18/h2-7,11-12,22,25H,8-10,21H2,1H3	UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.316	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50060426 (CHEMBL296161 | Dimethyl-[2-(5-[1,2,4]triazol-4-yl-...) Show SMILES CN(C)CCc1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C14H17N5/c1-18(2)6-5-11-8-15-14-4-3-12(7-13(11)14)19-9-16-17-10-19/h3-4,7-10,15H,5-6H2,1-2H3	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranes				Citation and Details BindingDB Entry DOI: 10.7270/Q2SX6GDH
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406757 (CHEMBL289489) Show SMILES CC(=O)Nc1ccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)cc1 Show InChI InChI=1S/C21H21N5O2/c1-13(27)24-17-5-2-14(3-6-17)10-20-25-21(28-26-20)15-4-7-19-18(11-15)16(8-9-22)12-23-19/h2-7,11-12,23H,8-10,22H2,1H3,(H,24,27)	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.501	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406756 (CHEMBL288880) Show SMILES CNC(=O)c1ccc(cc1)-c1noc(n1)-c1ccc2[nH]cc(CCN)c2c1 Show InChI InChI=1S/C20H19N5O2/c1-22-19(26)13-4-2-12(3-5-13)18-24-20(27-25-18)14-6-7-17-16(10-14)15(8-9-21)11-23-17/h2-7,10-11,23H,8-9,21H2,1H3,(H,22,26)	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.794	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406759 (CHEMBL39331) Show SMILES COc1ccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)cc1 Show InChI InChI=1S/C20H20N4O2/c1-25-16-5-2-13(3-6-16)10-19-23-20(26-24-19)14-4-7-18-17(11-14)15(8-9-21)12-22-18/h2-7,11-12,22H,8-10,21H2,1H3	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.794	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50213961 (CHEMBL53739) Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C16H19N5/c1-20-6-4-12(5-7-20)15-9-17-16-3-2-13(8-14(15)16)21-10-18-19-11-21/h2-3,8-12,17H,4-7H2,1H3	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranes				Citation and Details BindingDB Entry DOI: 10.7270/Q2SX6GDH
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406774 (CHEMBL262652) Show SMILES CN(C)CCc1c[nH]c2ccc(cc12)-c1nc(Cc2ccc(NS(C)(=O)=O)cc2)no1 Show InChI InChI=1S/C22H25N5O3S/c1-27(2)11-10-17-14-23-20-9-6-16(13-19(17)20)22-24-21(25-30-22)12-15-4-7-18(8-5-15)26-31(3,28)29/h4-9,13-14,23,26H,10-12H2,1-3H3	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406786 (CHEMBL40126) Show SMILES COc1cccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)c1 Show InChI InChI=1S/C20H20N4O2/c1-25-16-4-2-3-13(9-16)10-19-23-20(26-24-19)14-5-6-18-17(11-14)15(7-8-21)12-22-18/h2-6,9,11-12,22H,7-8,10,21H2,1H3	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406754 (CHEMBL37629) Show SMILES NCCc1c[nH]c2ccc(CCCc3nc(Cc4ccccc4)no3)cc12 Show InChI InChI=1S/C22H24N4O/c23-12-11-18-15-24-20-10-9-17(13-19(18)20)7-4-8-22-25-21(26-27-22)14-16-5-2-1-3-6-16/h1-3,5-6,9-10,13,15,24H,4,7-8,11-12,14,23H2	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406762 (CHEMBL37462) Show SMILES CN(C)CCc1c[nH]c2ccc(Cc3nc(N)ns3)cc12 Show InChI InChI=1S/C15H19N5S/c1-20(2)6-5-11-9-17-13-4-3-10(7-12(11)13)8-14-18-15(16)19-21-14/h3-4,7,9,17H,5-6,8H2,1-2H3,(H2,16,19)	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50060426 (CHEMBL296161 | Dimethyl-[2-(5-[1,2,4]triazol-4-yl-...) Show SMILES CN(C)CCc1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C14H17N5/c1-18(2)6-5-11-8-15-14-4-3-12(7-13(11)14)19-9-16-17-10-19/h3-4,7-10,15H,5-6H2,1-2H3	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranes				Citation and Details BindingDB Entry DOI: 10.7270/Q2SX6GDH
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406762 (CHEMBL37462) Show SMILES CN(C)CCc1c[nH]c2ccc(Cc3nc(N)ns3)cc12 Show InChI InChI=1S/C15H19N5S/c1-20(2)6-5-11-9-17-13-4-3-10(7-12(11)13)8-14-18-15(16)19-21-14/h3-4,7,9,17H,5-6,8H2,1-2H3,(H2,16,19)	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for the displacement of [3H]-5-HT to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranes				Bioorg Med Chem Lett 3: 993-997 (1993) Article DOI: 10.1016/S0960-894X(00)80274-7 BindingDB Entry DOI: 10.7270/Q2Z89DQV
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406779 (CHEMBL38104) Show SMILES CNC(=O)c1ccc(cc1)-c1noc(Cc2ccc3[nH]cc(CCN(C)C)c3c2)n1 Show InChI InChI=1S/C23H25N5O2/c1-24-23(29)17-7-5-16(6-8-17)22-26-21(30-27-22)13-15-4-9-20-19(12-15)18(14-25-20)10-11-28(2)3/h4-9,12,14,25H,10-11,13H2,1-3H3,(H,24,29)	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406778 (CHEMBL39158) Show SMILES CC(=O)Nc1ccc(Cc2noc(Cc3ccc4[nH]cc(CCN)c4c3)n2)cc1 Show InChI InChI=1S/C22H23N5O2/c1-14(28)25-18-5-2-15(3-6-18)11-21-26-22(29-27-21)12-16-4-7-20-19(10-16)17(8-9-23)13-24-20/h2-7,10,13,24H,8-9,11-12,23H2,1H3,(H,25,28)	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (GUINEA PIG)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus.				J Med Chem 35: 4503-5 (1992) Article DOI: 10.1021/jm00101a032 BindingDB Entry DOI: 10.7270/Q29C6WC5
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406776 (CHEMBL290706) Show SMILES CS(=O)(=O)Nc1ccc(Cc2noc(Cc3ccc4[nH]cc(CCN)c4c3)n2)cc1 Show InChI InChI=1S/C21H23N5O3S/c1-30(27,28)26-17-5-2-14(3-6-17)11-20-24-21(29-25-20)12-15-4-7-19-18(10-15)16(8-9-22)13-23-19/h2-7,10,13,23,26H,8-9,11-12,22H2,1H3	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM21392 (3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...) Show SMILES NCCc1c[nH]c2ccc(cc12)C(N)=O Show InChI InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15)	UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding activity against 5-hydroxytryptamine 1D receptor from pig caudate membrane using [3H]5-HT as radioligand				J Med Chem 38: 1799-810 (1995) Article DOI: 10.1021/jm00010a025 BindingDB Entry DOI: 10.7270/Q20V8DZS
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM21392 (3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...) Show SMILES NCCc1c[nH]c2ccc(cc12)C(N)=O Show InChI InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15)	UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406780 (CHEMBL288961) Show SMILES Cc1noc(CCCc2ccc3[nH]cc(CCN)c3c2)n1 Show InChI InChI=1S/C16H20N4O/c1-11-19-16(21-20-11)4-2-3-12-5-6-15-14(9-12)13(7-8-17)10-18-15/h5-6,9-10,18H,2-4,7-8,17H2,1H3	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406764 (CHEMBL39636) Show SMILES NCCc1c[nH]c2ccc(CCc3nc(Cc4ccccc4)no3)cc12 Show InChI InChI=1S/C21H22N4O/c22-11-10-17-14-23-19-8-6-16(12-18(17)19)7-9-21-24-20(25-26-21)13-15-4-2-1-3-5-15/h1-6,8,12,14,23H,7,9-11,13,22H2	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406768 (CHEMBL288821) Show SMILES NCCc1c[nH]c2ccc(cc12)-c1nc(Cc2ccccc2)no1 Show InChI InChI=1S/C19H18N4O/c20-9-8-15-12-21-17-7-6-14(11-16(15)17)19-22-18(23-24-19)10-13-4-2-1-3-5-13/h1-7,11-12,21H,8-10,20H2	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406772 (CHEMBL290657) Show SMILES CN(C)CCc1c[nH]c2ccc(cc12)-c1nc(Cc2ccccc2)no1 Show InChI InChI=1S/C21H22N4O/c1-25(2)11-10-17-14-22-19-9-8-16(13-18(17)19)21-23-20(24-26-21)12-15-6-4-3-5-7-15/h3-9,13-14,22H,10-12H2,1-2H3	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) Show SMILES CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3	UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents		n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound was tested for its ability to displace [125I]GTI binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranes				Citation and Details BindingDB Entry DOI: 10.7270/Q2SX6GDH
					More data for this Ligand-Target Pair
Serotonin 1d (5-HT1d) receptor (Sus scrofa)	BDBM50406761 (CHEMBL38482) Show SMILES NCCc1c[nH]c2ccc(cc12)-c1nc(no1)C1CC1 Show InChI InChI=1S/C15H16N4O/c16-6-5-11-8-17-13-4-3-10(7-12(11)13)15-18-14(19-20-15)9-1-2-9/h3-4,7-9,17H,1-2,5-6,16H2	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membrane				J Med Chem 36: 1529-38 (1993) Article DOI: 10.1021/jm00063a003 BindingDB Entry DOI: 10.7270/Q22V2HB9
					More data for this Ligand-Target Pair

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