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Compile Data Set for Download or QSAR

Found 98 hits Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase 1'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450346
PNG
(CHEMBL300883)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCN(CCCCCSc2nc(c([nH]2)-c2ccc(OC)cc2)-c2ccc(OC)cc2)C(=O)NC(C)C)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C48H58N6O5S2/c1-33(2)49-48(55)54(29-9-7-11-31-60-46-50-42(34-13-21-38(56-3)22-14-34)43(51-46)35-15-23-39(57-4)24-16-35)30-10-8-12-32-61-47-52-44(36-17-25-40(58-5)26-18-36)45(53-47)37-19-27-41(59-6)28-20-37/h13-28,33H,7-12,29-32H2,1-6H3,(H,49,55)(H,50,51)(H,52,53)
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TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 1


(Cricetulus griseus)
BDBM50051901
PNG
(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Show SMILES Cc1cc(C)n(CCCCCSc2nc(c([nH]2)-c2ccccc2)-c2ccccc2)n1
Show InChI InChI=1S/C25H28N4S/c1-19-18-20(2)29(28-19)16-10-5-11-17-30-25-26-23(21-12-6-3-7-13-21)24(27-25)22-14-8-4-9-15-22/h3-4,6-9,12-15,18H,5,10-11,16-17H2,1-2H3,(H,26,27)
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TBA

Curated by ChEMBL


Assay Description
Concentration required for the inhibition of Cholesterol O-acyl transferase from hamster liver


Bioorg Med Chem Lett 2: 375-380 (1992)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285443
PNG
(Benzooxazol-2-yl-[5-(4,5-diphenyl-1H-imidazol-2-yl...)
Show SMILES CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)c1nc2ccccc2o1
Show InChI InChI=1S/C34H40N4OS/c1-2-3-4-5-15-24-38(34-35-29-22-13-14-23-30(29)39-34)25-16-8-17-26-40-33-36-31(27-18-9-6-10-19-27)32(37-33)28-20-11-7-12-21-28/h6-7,9-14,18-23H,2-5,8,15-17,24-26H2,1H3,(H,36,37)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285435
PNG
(Benzooxazol-2-yl-{5-[4,5-bis-(4-dimethylamino-phen...)
Show SMILES CCN(CCCCCSc1nc(c([nH]1)-c1ccc(cc1)N(C)C)-c1ccc(cc1)N(C)C)c1nc2ccccc2o1
Show InChI InChI=1S/C33H40N6OS/c1-6-39(33-34-28-12-8-9-13-29(28)40-33)22-10-7-11-23-41-32-35-30(24-14-18-26(19-15-24)37(2)3)31(36-32)25-16-20-27(21-17-25)38(4)5/h8-9,12-21H,6-7,10-11,22-23H2,1-5H3,(H,35,36)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285432
PNG
(1N,1N-dimethyl-4-[2-{5-[4,5-di(4-dimethylaminophen...)
Show SMILES CN(C)c1ccc(cc1)-c1nc(SCCCCCSc2nc(c([nH]2)-c2ccc(cc2)N(C)C)-c2ccc(cc2)N(C)C)[nH]c1-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C43H52N8S2/c1-48(2)34-20-12-30(13-21-34)38-39(31-14-22-35(23-15-31)49(3)4)45-42(44-38)52-28-10-9-11-29-53-43-46-40(32-16-24-36(25-17-32)50(5)6)41(47-43)33-18-26-37(27-19-33)51(7)8/h12-27H,9-11,28-29H2,1-8H3,(H,44,45)(H,46,47)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450357
PNG
(CHEMBL48164)
Show SMILES CC(C)NC(=O)N(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)CCCCCSc1nc(c([nH]1)-c1ccc(cc1)N(C)C)-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C48H60N8OS2/c1-35(2)49-48(57)56(31-15-9-17-33-58-46-50-42(36-19-11-7-12-20-36)43(51-46)37-21-13-8-14-22-37)32-16-10-18-34-59-47-52-44(38-23-27-40(28-24-38)54(3)4)45(53-47)39-25-29-41(30-26-39)55(5)6/h7-8,11-14,19-30,35H,9-10,15-18,31-34H2,1-6H3,(H,49,57)(H,50,51)(H,52,53)
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TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450361
PNG
(CHEMBL300913)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCN(Cc2ccccn2)C(=O)NC(C)C)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C32H39N5O3S/c1-23(2)34-32(38)37(22-26-10-6-7-19-33-26)20-8-5-9-21-41-31-35-29(24-11-15-27(39-3)16-12-24)30(36-31)25-13-17-28(40-4)18-14-25/h6-7,10-19,23H,5,8-9,20-22H2,1-4H3,(H,34,38)(H,35,36)
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TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285420
PNG
(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Show SMILES CCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2ccccc2o1
Show InChI InChI=1S/C33H38N4O3S/c1-4-5-21-37(33-34-28-11-7-8-12-29(28)40-33)22-9-6-10-23-41-32-35-30(24-13-17-26(38-2)18-14-24)31(36-32)25-15-19-27(39-3)20-16-25/h7-8,11-20H,4-6,9-10,21-23H2,1-3H3,(H,35,36)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285447
PNG
(CHEMBL53397 | {5-[4,5-Bis-(4-methoxy-phenyl)-1H-im...)
Show SMILES CCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2cc(ccc2o1)C(C)(C)C
Show InChI InChI=1S/C37H46N4O3S/c1-7-8-22-41(36-38-31-25-28(37(2,3)4)16-21-32(31)44-36)23-10-9-11-24-45-35-39-33(26-12-17-29(42-5)18-13-26)34(40-35)27-14-19-30(43-6)20-15-27/h12-21,25H,7-11,22-24H2,1-6H3,(H,39,40)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285434
PNG
(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Show SMILES COCCOCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2ccccc2o1
Show InChI InChI=1S/C34H40N4O5S/c1-39-22-23-42-21-20-38(34-35-29-9-5-6-10-30(29)43-34)19-7-4-8-24-44-33-36-31(25-11-15-27(40-2)16-12-25)32(37-33)26-13-17-28(41-3)18-14-26/h5-6,9-18H,4,7-8,19-24H2,1-3H3,(H,36,37)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285444
PNG
(1N,1N-dimethyl-4-{5-(4-dimethylaminophenyl)-2-[5-(...)
Show SMILES CC(C)c1nc2ccccc2n1CCCCCSc1nc(c([nH]1)-c1ccc(cc1)N(C)C)-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C34H42N6S/c1-24(2)33-35-29-12-8-9-13-30(29)40(33)22-10-7-11-23-41-34-36-31(25-14-18-27(19-15-25)38(3)4)32(37-34)26-16-20-28(21-17-26)39(5)6/h8-9,12-21,24H,7,10-11,22-23H2,1-6H3,(H,36,37)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285442
PNG
(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Show SMILES CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2ccccc2o1
Show InChI InChI=1S/C36H44N4O3S/c1-4-5-6-7-11-24-40(36-37-31-14-9-10-15-32(31)43-36)25-12-8-13-26-44-35-38-33(27-16-20-29(41-2)21-17-27)34(39-35)28-18-22-30(42-3)23-19-28/h9-10,14-23H,4-8,11-13,24-26H2,1-3H3,(H,38,39)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450366
PNG
(CHEMBL49265)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCN(CCc2ccccn2)C(=O)NC(C)C)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C33H41N5O3S/c1-24(2)35-33(39)38(22-19-27-10-6-7-20-34-27)21-8-5-9-23-42-32-36-30(25-11-15-28(40-3)16-12-25)31(37-32)26-13-17-29(41-4)18-14-26/h6-7,10-18,20,24H,5,8-9,19,21-23H2,1-4H3,(H,35,39)(H,36,37)
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TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285430
PNG
(Benzooxazol-2-yl-{5-[4,5-bis-(4-dimethylamino-phen...)
Show SMILES CN(C)c1ccc(cc1)-c1nc(SCCCCCNc2nc3ccccc3o2)[nH]c1-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C31H36N6OS/c1-36(2)24-16-12-22(13-17-24)28-29(23-14-18-25(19-15-23)37(3)4)35-31(34-28)39-21-9-5-8-20-32-30-33-26-10-6-7-11-27(26)38-30/h6-7,10-19H,5,8-9,20-21H2,1-4H3,(H,32,33)(H,34,35)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285427
PNG
(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Show SMILES CCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2ccccc2o1
Show InChI InChI=1S/C31H34N4O3S/c1-4-35(31-32-26-10-6-7-11-27(26)38-31)20-8-5-9-21-39-30-33-28(22-12-16-24(36-2)17-13-22)29(34-30)23-14-18-25(37-3)19-15-23/h6-7,10-19H,4-5,8-9,20-21H2,1-3H3,(H,33,34)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50051901
PNG
(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Show SMILES Cc1cc(C)n(CCCCCSc2nc(c([nH]2)-c2ccccc2)-c2ccccc2)n1
Show InChI InChI=1S/C25H28N4S/c1-19-18-20(2)29(28-19)16-10-5-11-17-30-25-26-23(21-12-6-3-7-13-21)24(27-25)22-14-8-4-9-15-22/h3-4,6-9,12-15,18H,5,10-11,16-17H2,1-2H3,(H,26,27)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450345
PNG
(CHEMBL51643)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCN(CCCCCSc2nc(c([nH]2)-c2ccccc2)-c2ccccc2)C(=O)NC(C)C)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C46H54N6O3S2/c1-33(2)47-46(53)52(29-13-7-15-31-56-44-48-40(34-17-9-5-10-18-34)41(49-44)35-19-11-6-12-20-35)30-14-8-16-32-57-45-50-42(36-21-25-38(54-3)26-22-36)43(51-45)37-23-27-39(55-4)28-24-37/h5-6,9-12,17-28,33H,7-8,13-16,29-32H2,1-4H3,(H,47,53)(H,48,49)(H,50,51)
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TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450364
PNG
(CHEMBL50171)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCN(Cc2ccccn2)C(=O)Nc2ccc(F)cc2F)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C35H35F2N5O3S/c1-44-28-14-9-24(10-15-28)32-33(25-11-16-29(45-2)17-12-25)41-34(40-32)46-21-7-3-6-20-42(23-27-8-4-5-19-38-27)35(43)39-31-18-13-26(36)22-30(31)37/h4-5,8-19,22H,3,6-7,20-21,23H2,1-2H3,(H,39,43)(H,40,41)
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TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285419
PNG
(2-{5-[4,5-di(4-methoxyphenyl)-1H-2-imidazolylsulfa...)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCSc2nc(c([nH]2)-c2ccc(OC)cc2)-c2ccc(OC)cc2)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C39H40N4O4S2/c1-44-30-16-8-26(9-17-30)34-35(27-10-18-31(45-2)19-11-27)41-38(40-34)48-24-6-5-7-25-49-39-42-36(28-12-20-32(46-3)21-13-28)37(43-39)29-14-22-33(47-4)23-15-29/h8-23H,5-7,24-25H2,1-4H3,(H,40,41)(H,42,43)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50287517
PNG
(3-(2,6-Diisopropyl-phenyl)-1-(2-dodecyl-2H-tetrazo...)
Show SMILES CCCCCCCCCCCCn1nnc(n1)N(C(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccccc1
Show InChI InChI=1S/C32H48N6O/c1-6-7-8-9-10-11-12-13-14-18-24-37-35-31(34-36-37)38(27-20-16-15-17-21-27)32(39)33-30-28(25(2)3)22-19-23-29(30)26(4)5/h15-17,19-23,25-26H,6-14,18,24H2,1-5H3,(H,33,39)
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TBA

Curated by ChEMBL


Assay Description
Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)


Bioorg Med Chem Lett 6: 1753-1758 (1996)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285433
PNG
(1N,1N-dimethyl-4-{5-(4-dimethylaminophenyl)-2-[5-(...)
Show SMILES CN(C)c1ccc(cc1)-c1nc(SCCCCCn2nc(C)cc2C)[nH]c1-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C29H38N6S/c1-21-20-22(2)35(32-21)18-8-7-9-19-36-29-30-27(23-10-14-25(15-11-23)33(3)4)28(31-29)24-12-16-26(17-13-24)34(5)6/h10-17,20H,7-9,18-19H2,1-6H3,(H,30,31)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285428
PNG
(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCn2c(nc3ccccc23)C(C)C)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C32H36N4O2S/c1-22(2)31-33-27-10-6-7-11-28(27)36(31)20-8-5-9-21-39-32-34-29(23-12-16-25(37-3)17-13-23)30(35-32)24-14-18-26(38-4)19-15-24/h6-7,10-19,22H,5,8-9,20-21H2,1-4H3,(H,34,35)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450348
PNG
(CHEMBL51282)
Show SMILES CN(C)c1ccc(cc1)-c1nc(SCCOCCSc2nc(c([nH]2)-c2ccc(cc2)N(C)C)-c2ccc(cc2)N(C)C)[nH]c1-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C42H50N8OS2/c1-47(2)33-17-9-29(10-18-33)37-38(30-11-19-34(20-12-30)48(3)4)44-41(43-37)52-27-25-51-26-28-53-42-45-39(31-13-21-35(22-14-31)49(5)6)40(46-42)32-15-23-36(24-16-32)50(7)8/h9-24H,25-28H2,1-8H3,(H,43,44)(H,45,46)
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TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50005944
PNG
(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Show SMILES CCCCCCCCCCC(C)(C)C(=O)Nc1c(OC)cc(OC)cc1OC
Show InChI InChI=1S/C23H39NO4/c1-7-8-9-10-11-12-13-14-15-23(2,3)22(25)24-21-19(27-5)16-18(26-4)17-20(21)28-6/h16-17H,7-15H2,1-6H3,(H,24,25)
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TBA

Curated by ChEMBL


Assay Description
Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)


Bioorg Med Chem Lett 6: 1753-1758 (1996)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450347
PNG
(CHEMBL431940)
Show SMILES CN(C)c1ccc(cc1)-c1nc(SCCCCCN(CCCCCSc2nc(c([nH]2)-c2ccccc2)-c2ccccc2)C(=O)Nc2ccc(F)cc2F)[nH]c1-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C51H56F2N8OS2/c1-59(2)41-26-21-38(22-27-41)47-48(39-23-28-42(29-24-39)60(3)4)58-50(57-47)64-34-16-8-14-32-61(51(62)54-44-30-25-40(52)35-43(44)53)31-13-7-15-33-63-49-55-45(36-17-9-5-10-18-36)46(56-49)37-19-11-6-12-20-37/h5-6,9-12,17-30,35H,7-8,13-16,31-34H2,1-4H3,(H,54,62)(H,55,56)(H,57,58)
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TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285425
PNG
((1H-Benzoimidazol-2-yl)-{5-[4,5-bis-(4-methoxy-phe...)
Show SMILES CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2ccccc2[nH]1
Show InChI InChI=1S/C36H45N5O2S/c1-4-5-6-7-11-24-41(35-37-31-14-9-10-15-32(31)38-35)25-12-8-13-26-44-36-39-33(27-16-20-29(42-2)21-17-27)34(40-36)28-18-22-30(43-3)23-19-28/h9-10,14-23H,4-8,11-13,24-26H2,1-3H3,(H,37,38)(H,39,40)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285424
PNG
(Benzooxazol-2-yl-{4-[4,5-bis-(4-methoxy-phenyl)-1H...)
Show SMILES CCCCCCCN(CCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2ccccc2o1
Show InChI InChI=1S/C35H42N4O3S/c1-4-5-6-7-10-23-39(35-36-30-13-8-9-14-31(30)42-35)24-11-12-25-43-34-37-32(26-15-19-28(40-2)20-16-26)33(38-34)27-17-21-29(41-3)22-18-27/h8-9,13-22H,4-7,10-12,23-25H2,1-3H3,(H,37,38)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285418
PNG
(Benzooxazol-2-yl-ethyl-{5-[5-(4-methylsulfanyl-phe...)
Show SMILES CCN(CCCCCSc1nc(c([nH]1)-c1ccc(SC)cc1)-c1ccccc1)c1nc2ccccc2o1
Show InChI InChI=1S/C30H32N4OS2/c1-3-34(30-31-25-14-8-9-15-26(25)35-30)20-10-5-11-21-37-29-32-27(22-12-6-4-7-13-22)28(33-29)23-16-18-24(36-2)19-17-23/h4,6-9,12-19H,3,5,10-11,20-21H2,1-2H3,(H,32,33)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285422
PNG
((1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yl...)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCn2c(Nc3ccccc3)nc3ccccc23)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C35H35N5O2S/c1-41-28-19-15-25(16-20-28)32-33(26-17-21-29(42-2)22-18-26)39-35(38-32)43-24-10-4-9-23-40-31-14-8-7-13-30(31)37-34(40)36-27-11-5-3-6-12-27/h3,5-8,11-22H,4,9-10,23-24H2,1-2H3,(H,36,37)(H,38,39)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285421
PNG
(Benzothiazol-2-yl-[5-(4,5-diphenyl-1H-imidazol-2-y...)
Show SMILES CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)c1nc2ccccc2s1
Show InChI InChI=1S/C34H40N4S2/c1-2-3-4-5-15-24-38(34-35-29-22-13-14-23-30(29)40-34)25-16-8-17-26-39-33-36-31(27-18-9-6-10-19-27)32(37-33)28-20-11-7-12-21-28/h6-7,9-14,18-23H,2-5,8,15-17,24-26H2,1H3,(H,36,37)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450367
PNG
(CHEMBL48383)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCN(CCc2ccccn2)C(=O)Nc2ccc(F)cc2F)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C36H37F2N5O3S/c1-45-29-14-9-25(10-15-29)33-34(26-11-16-30(46-2)17-12-26)42-35(41-33)47-23-7-3-6-21-43(22-19-28-8-4-5-20-39-28)36(44)40-32-18-13-27(37)24-31(32)38/h4-5,8-18,20,24H,3,6-7,19,21-23H2,1-2H3,(H,40,44)(H,41,42)
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TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285439
PNG
(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Show SMILES CC(C)c1nc2ccccc2n1CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C30H32N4S/c1-22(2)29-31-25-18-10-11-19-26(25)34(29)20-12-5-13-21-35-30-32-27(23-14-6-3-7-15-23)28(33-30)24-16-8-4-9-17-24/h3-4,6-11,14-19,22H,5,12-13,20-21H2,1-2H3,(H,32,33)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450362
PNG
(CHEMBL297241)
Show SMILES Fc1ccc(NC(=O)N(CCCCCSc2nc(c([nH]2)-c2ccccc2)-c2ccccc2)c2ccccn2)c(F)c1
Show InChI InChI=1S/C32H29F2N5OS/c33-25-17-18-27(26(34)22-25)36-32(40)39(28-16-8-9-19-35-28)20-10-3-11-21-41-31-37-29(23-12-4-1-5-13-23)30(38-31)24-14-6-2-7-15-24/h1-2,4-9,12-19,22H,3,10-11,20-21H2,(H,36,40)(H,37,38)
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TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285431
PNG
(2-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCSc2nc3ccccc3[nH]2)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C29H30N4O2S2/c1-34-22-14-10-20(11-15-22)26-27(21-12-16-23(35-2)17-13-21)33-29(32-26)37-19-7-3-6-18-36-28-30-24-8-4-5-9-25(24)31-28/h4-5,8-17H,3,6-7,18-19H2,1-2H3,(H,30,31)(H,32,33)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285437
PNG
(8-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCSc2nc3ncncc3[nH]2)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C27H28N6O2S2/c1-34-20-10-6-18(7-11-20)23-24(19-8-12-21(35-2)13-9-19)32-27(31-23)37-15-5-3-4-14-36-26-30-22-16-28-17-29-25(22)33-26/h6-13,16-17H,3-5,14-15H2,1-2H3,(H,31,32)(H,28,29,30,33)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50287518
PNG
(1-(2-Dodecyl-2H-tetrazol-5-yl)-1-phenyl-3-(2,4,6-t...)
Show SMILES CCCCCCCCCCCCn1nnc(n1)N(C(=O)Nc1c(OC)cc(OC)cc1OC)c1ccccc1
Show InChI InChI=1S/C29H42N6O4/c1-5-6-7-8-9-10-11-12-13-17-20-34-32-28(31-33-34)35(23-18-15-14-16-19-23)29(36)30-27-25(38-3)21-24(37-2)22-26(27)39-4/h14-16,18-19,21-22H,5-13,17,20H2,1-4H3,(H,30,36)
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TBA

Curated by ChEMBL


Assay Description
Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)


Bioorg Med Chem Lett 6: 1753-1758 (1996)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450365
PNG
(CHEMBL298651)
Show SMILES CC(C)NC(=O)N(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)c1ccccn1
Show InChI InChI=1S/C29H33N5OS/c1-22(2)31-29(35)34(25-18-10-11-19-30-25)20-12-5-13-21-36-28-32-26(23-14-6-3-7-15-23)27(33-28)24-16-8-4-9-17-24/h3-4,6-11,14-19,22H,5,12-13,20-21H2,1-2H3,(H,31,35)(H,32,33)
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TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285423
PNG
(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Show SMILES COc1ccc(cc1)-c1nc(SCCCCCn2c(SC)nc3ccccc23)[nH]c1-c1ccc(OC)cc1
Show InChI InChI=1S/C30H32N4O2S2/c1-35-23-15-11-21(12-16-23)27-28(22-13-17-24(36-2)18-14-22)33-29(32-27)38-20-8-4-7-19-34-26-10-6-5-9-25(26)31-30(34)37-3/h5-6,9-18H,4,7-8,19-20H2,1-3H3,(H,32,33)
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n/an/a 950n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50033969
PNG
(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Show SMILES CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C34H40F2N4OS/c1-2-3-4-5-13-22-40(34(41)37-30-21-20-28(35)25-29(30)36)23-14-8-15-24-42-33-38-31(26-16-9-6-10-17-26)32(39-33)27-18-11-7-12-19-27/h6-7,9-12,16-21,25H,2-5,8,13-15,22-24H2,1H3,(H,37,41)(H,38,39)
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n/an/a 1.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50033969
PNG
(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Show SMILES CCCCCCCN(CCCCCSc1nc(c([nH]1)-c1ccccc1)-c1ccccc1)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C34H40F2N4OS/c1-2-3-4-5-13-22-40(34(41)37-30-21-20-28(35)25-29(30)36)23-14-8-15-24-42-33-38-31(26-16-9-6-10-17-26)32(39-33)27-18-11-7-12-19-27/h6-7,9-12,16-21,25H,2-5,8,13-15,22-24H2,1H3,(H,37,41)(H,38,39)
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n/an/a 1.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50285438
PNG
(CHEMBL299338 | {5-[4,5-Bis-(4-methoxy-phenyl)-1H-i...)
Show SMILES CCCCN(CCCCCSc1nc(c([nH]1)-c1ccc(OC)cc1)-c1ccc(OC)cc1)c1nc2cc(Cl)c(cc2o1)[N+]([O-])=O
Show InChI InChI=1S/C33H36ClN5O5S/c1-4-5-17-38(33-35-27-20-26(34)28(39(40)41)21-29(27)44-33)18-7-6-8-19-45-32-36-30(22-9-13-24(42-2)14-10-22)31(37-32)23-11-15-25(43-3)16-12-23/h9-16,20-21H,4-8,17-19H2,1-3H3,(H,36,37)
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n/an/a 1.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell culture


Bioorg Med Chem Lett 5: 177-180 (1995)

More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450324
PNG
(CHEMBL45913)
Show SMILES CCCCCCN(CCCCCSc1nc2c([nH]1)n(C)c(=O)n(C)c2=O)C(=O)NC(C)C
Show InChI InChI=1S/C22H38N6O3S/c1-6-7-8-10-13-28(21(30)23-16(2)3)14-11-9-12-15-32-20-24-17-18(25-20)26(4)22(31)27(5)19(17)29/h16H,6-15H2,1-5H3,(H,23,30)(H,24,25)
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n/an/a 1.53E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50037632
PNG
(3-(2,4-Difluoro-phenyl)-1-heptyl-1-[5-(4-phenyl-1H...)
Show SMILES CCCCCCCN(CCCCCSc1nc(c[nH]1)-c1ccccc1)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C28H36F2N4OS/c1-2-3-4-5-10-17-34(28(35)33-25-16-15-23(29)20-24(25)30)18-11-7-12-19-36-27-31-21-26(32-27)22-13-8-6-9-14-22/h6,8-9,13-16,20-21H,2-5,7,10-12,17-19H2,1H3,(H,31,32)(H,33,35)
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n/an/a 1.60E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450323
PNG
(CHEMBL46017)
Show SMILES CCCCCCN(CCCCCSc1nc2cc(C)ccc2[nH]1)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C26H34F2N4OS/c1-3-4-5-7-14-32(26(33)31-22-13-11-20(27)18-21(22)28)15-8-6-9-16-34-25-29-23-12-10-19(2)17-24(23)30-25/h10-13,17-18H,3-9,14-16H2,1-2H3,(H,29,30)(H,31,33)
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n/an/a 2.06E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450320
PNG
(CHEMBL49001)
Show SMILES CCCCCCCN(CCCCCSC1=NC(=O)C(N1)(c1ccccc1)c1ccccc1)C(=O)NC(C)C
Show InChI InChI=1S/C31H44N4O2S/c1-4-5-6-7-15-22-35(30(37)32-25(2)3)23-16-10-17-24-38-29-33-28(36)31(34-29,26-18-11-8-12-19-26)27-20-13-9-14-21-27/h8-9,11-14,18-21,25H,4-7,10,15-17,22-24H2,1-3H3,(H,32,37)(H,33,34,36)
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n/an/a 2.14E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450350
PNG
(CHEMBL48500)
Show SMILES Fc1ccc(NC(=O)N(CCCCCSc2nc(c([nH]2)-c2ccccc2)-c2ccccc2)CCc2ccccn2)c(F)c1
Show InChI InChI=1S/C34H33F2N5OS/c35-27-17-18-30(29(36)24-27)38-34(42)41(22-19-28-16-8-9-20-37-28)21-10-3-11-23-43-33-39-31(25-12-4-1-5-13-25)32(40-33)26-14-6-2-7-15-26/h1-2,4-9,12-18,20,24H,3,10-11,19,21-23H2,(H,38,42)(H,39,40)
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n/an/a 2.44E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450313
PNG
(CHEMBL46174)
Show SMILES CCCCCCN(CCCCCSc1nc2CCCCc2[nH]1)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C25H36F2N4OS/c1-2-3-4-8-15-31(25(32)30-21-14-13-19(26)18-20(21)27)16-9-5-10-17-33-24-28-22-11-6-7-12-23(22)29-24/h13-14,18H,2-12,15-17H2,1H3,(H,28,29)(H,30,32)
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n/an/a 2.58E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450336
PNG
(CHEMBL45964)
Show SMILES CCCCCCN(CCCCCSc1nc2ccccc2s1)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C25H31F2N3OS2/c1-2-3-4-8-15-30(24(31)28-21-14-13-19(26)18-20(21)27)16-9-5-10-17-32-25-29-22-11-6-7-12-23(22)33-25/h6-7,11-14,18H,2-5,8-10,15-17H2,1H3,(H,28,31)
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n/an/a 2.73E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450322
PNG
(CHEMBL431934)
Show SMILES CCCCCCCN(CCCCCOC1=NC(S)=NC1(c1ccccc1)c1ccccc1)C(=O)NC(C)C
Show InChI InChI=1S/C31H44N4O2S/c1-4-5-6-7-15-22-35(30(36)32-25(2)3)23-16-10-17-24-37-28-31(34-29(38)33-28,26-18-11-8-12-19-26)27-20-13-9-14-21-27/h8-9,11-14,18-21,25H,4-7,10,15-17,22-24H2,1-3H3,(H,32,36)(H,34,38)
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n/an/a 2.79E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.


Citation and Details
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Mus musculus)
BDBM50450360
PNG
(CHEMBL49855)
Show SMILES CN(C)c1ccc(cc1)-c1nc(SCCOCCSc2[nH]cnc3ncnc23)[nH]c1-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C28H32N8OS2/c1-35(2)21-9-5-19(6-10-21)23-24(20-7-11-22(12-8-20)36(3)4)34-28(33-23)39-16-14-37-13-15-38-27-25-26(30-17-29-25)31-18-32-27/h5-12,17-18H,13-16H2,1-4H3,(H,33,34)(H,29,30,31,32)
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n/an/a 2.99E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture


Citation and Details
More data for this
Ligand-Target Pair
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