BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 208 hits Enz. Inhib. hit(s) with Target = 'Thioredoxin'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thioredoxin reductase (TrxR)


(Escherichia coli (strain K12))
BDBM50385299
PNG
(CHEMBL2035464 | US8592468, EbSe16)
Show SMILES O=c1n(CCCCCCn2[se]c3ccccc3c2=O)[se]c2ccccc12
Show InChI InChI=1S/C20H20N2O2Se2/c23-19-15-9-3-5-11-17(15)25-21(19)13-7-1-2-8-14-22-20(24)16-10-4-6-12-18(16)26-22/h3-6,9-12H,1-2,7-8,13-14H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
10n/a 2.25E+3n/an/an/an/an/an/a



Thioredoxin Systems AB

US Patent


Assay Description
All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB ...


US Patent US8592468 (2013)

More data for this
Ligand-Target Pair
Thioredoxin reductase (TrxR)


(Escherichia coli (strain K12))
BDBM50385302
PNG
(CHEMBL2035461 | US8592468, EbSe15)
Show SMILES O=c1n(CCCn2[se]c3ccccc3c2=O)[se]c2ccccc12
Show InChI InChI=1S/C17H14N2O2Se2/c20-16-12-6-1-3-8-14(12)22-18(16)10-5-11-19-17(21)13-7-2-4-9-15(13)23-19/h1-4,6-9H,5,10-11H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
40n/a 2.10E+3n/an/an/an/an/an/a



Thioredoxin Systems AB

US Patent


Assay Description
All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB ...


US Patent US8592468 (2013)

More data for this
Ligand-Target Pair
Thioredoxin reductase (TrxR)


(Escherichia coli (strain K12))
BDBM50385303
PNG
(CHEMBL2035460 | US8592468, EbSe14)
Show SMILES O=c1n(CCn2[se]c3ccccc3c2=O)[se]c2ccccc12
Show InChI InChI=1S/C16H12N2O2Se2/c19-15-11-5-1-3-7-13(11)21-17(15)9-10-18-16(20)12-6-2-4-8-14(12)22-18/h1-8H,9-10H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
50n/a 2.00E+3n/an/an/an/an/an/a



Thioredoxin Systems AB

US Patent


Assay Description
All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB ...


US Patent US8592468 (2013)

More data for this
Ligand-Target Pair
Thioredoxin reductase 2


(Plasmodium falciparum (isolate 3D7))
BDBM50182122
PNG
(CHEMBL204688 | bis(2,4-dinitrophenyl)sulfane)
Show SMILES [O-][N+](=O)c1ccc(Sc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C12H6N4O8S/c17-13(18)7-1-3-11(9(5-7)15(21)22)25-12-4-2-8(14(19)20)6-10(12)16(23)24/h1-6H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

AffyNet 
Article
PubMed
200n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to Plasmodium falciparum TrxR in presence of NADPH


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 2


(Plasmodium falciparum (isolate 3D7))
BDBM50182122
PNG
(CHEMBL204688 | bis(2,4-dinitrophenyl)sulfane)
Show SMILES [O-][N+](=O)c1ccc(Sc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C12H6N4O8S/c17-13(18)7-1-3-11(9(5-7)15(21)22)25-12-4-2-8(14(19)20)6-10(12)16(23)24/h1-6H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

AffyNet 
Article
PubMed
200n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to Plasmodium falciparum TrxR in presence of thioredoxin


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase (TrxR)


(Escherichia coli (strain K12))
BDBM106948
PNG
(US8592468, EbSe12)
Show SMILES [O-][N+](=O)c1cccnc1-n1[se]c2ccccc2c1=O
Show InChI InChI=1S/C12H7N3O3Se/c16-12-8-4-1-2-6-10(8)19-14(12)11-9(15(17)18)5-3-7-13-11/h1-7H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
250n/a 3.00E+3n/an/an/an/an/an/a



Thioredoxin Systems AB

US Patent


Assay Description
All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB ...


US Patent US8592468 (2013)

More data for this
Ligand-Target Pair
Thioredoxin reductase (TrxR)


(Escherichia coli (strain K12))
BDBM106941
PNG
(US8592468, EbSe8)
Show SMILES Cc1cc(Cl)ccc1-n1[se]c2ccccc2c1=O
Show InChI InChI=1S/C14H10ClNOSe/c1-9-8-10(15)6-7-12(9)16-14(17)11-4-2-3-5-13(11)18-16/h2-8H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
250n/a 6.00E+3n/an/an/an/an/an/a



Thioredoxin Systems AB

US Patent


Assay Description
All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB ...


US Patent US8592468 (2013)

More data for this
Ligand-Target Pair
Thioredoxin reductase (TrxR)


(Escherichia coli (strain K12))
BDBM34233
PNG
(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Show SMILES O=c1n([se]c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
US Patent
300n/a 6.00E+3n/an/an/an/an/an/a



Thioredoxin Systems AB

US Patent


Assay Description
All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB ...


US Patent US8592468 (2013)

More data for this
Ligand-Target Pair
Thioredoxin reductase (TrxR)


(Escherichia coli (strain K12))
BDBM106940
PNG
(US8592468, EbSe7)
Show SMILES Clc1ccc(cc1)-n1[se]c2ccccc2c1=O
Show InChI InChI=1S/C13H8ClNOSe/c14-9-5-7-10(8-6-9)15-13(16)11-3-1-2-4-12(11)17-15/h1-8H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
550n/a 7.00E+3n/an/an/an/an/an/a



Thioredoxin Systems AB

US Patent


Assay Description
All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB ...


US Patent US8592468 (2013)

More data for this
Ligand-Target Pair
Thioredoxin reductase 2


(Plasmodium falciparum (isolate 3D7))
BDBM50182128
PNG
(4-nitrobenzo[c][1,2,5]thiadiazole | CHEMBL383084)
Show SMILES [O-][N+](=O)c1cccc2nsnc12
Show InChI InChI=1S/C6H3N3O2S/c10-9(11)5-3-1-2-4-6(5)8-12-7-4/h1-3H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
650n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to Plasmodium falciparum TrxR in presence of thioredoxin


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase (TrxR)


(Escherichia coli (strain K12))
BDBM106944
PNG
(US8592468, EbSe2)
Show SMILES O=c1[nH][se]c2ccccc12
Show InChI InChI=1S/C7H5NOSe/c9-7-5-3-1-2-4-6(5)10-8-7/h1-4H,(H,8,9)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
1.00E+3n/a 1.50E+4n/an/an/an/an/an/a



Thioredoxin Systems AB

US Patent


Assay Description
All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB ...


US Patent US8592468 (2013)

More data for this
Ligand-Target Pair
Thioredoxin reductase 2


(Plasmodium falciparum (isolate 3D7))
BDBM50182128
PNG
(4-nitrobenzo[c][1,2,5]thiadiazole | CHEMBL383084)
Show SMILES [O-][N+](=O)c1cccc2nsnc12
Show InChI InChI=1S/C6H3N3O2S/c10-9(11)5-3-1-2-4-6(5)8-12-7-4/h1-3H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
1.00E+3n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to Plasmodium falciparum TrxR in presence of NADPH


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase (TrxR)


(Escherichia coli (strain K12))
BDBM106942
PNG
(US8592468, EbSe9)
Show SMILES O=COc1ccccc1-n1[se]c2ccccc2c1=O
Show InChI InChI=1S/C14H9NO3Se/c16-9-18-12-7-3-2-6-11(12)15-14(17)10-5-1-4-8-13(10)19-15/h1-9H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
1.20E+3n/a 7.50E+3n/an/an/an/an/an/a



Thioredoxin Systems AB

US Patent


Assay Description
All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB ...


US Patent US8592468 (2013)

More data for this
Ligand-Target Pair
Thioredoxin, mitochondrial


(Homo sapiens)
BDBM50366237
PNG
(GAMBOGIC ACID)
Show SMILES CC(C)=CCC[C@@]1(C)Oc2c(CC=C(C)C)c3O[C@@]45[C@H]6C[C@@H](C=C4C(=O)c3c(O)c2C=C1)C(=O)[C@]5(C\C=C(\C)C(O)=O)OC6(C)C
Show InChI InChI=1S/C38H44O8/c1-20(2)10-9-15-36(8)16-14-24-29(39)28-30(40)26-18-23-19-27-35(6,7)46-37(33(23)41,17-13-22(5)34(42)43)38(26,27)45-32(28)25(31(24)44-36)12-11-21(3)4/h10-11,13-14,16,18,23,27,39H,9,12,15,17,19H2,1-8H3,(H,42,43)/b22-13-/t23-,27+,36-,37+,38-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
1.31E+3n/an/an/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant TRX-2 up to 60 mins by insulin reduction assay


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase (TrxR)


(Escherichia coli (strain K12))
BDBM106949
PNG
(US8592468, EbSe13)
Show SMILES O=c1n([se]c2ccccc12)-c1ccncc1
Show InChI InChI=1S/C12H8N2OSe/c15-12-10-3-1-2-4-11(10)16-14(12)9-5-7-13-8-6-9/h1-8H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
1.50E+3n/a 3.00E+3n/an/an/an/an/an/a



Thioredoxin Systems AB

US Patent


Assay Description
All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB ...


US Patent US8592468 (2013)

More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50333880
PNG
(CHEMBL1614664 | Hypericin | Pseudohypericin)
Show SMILES Cc1cc(O)c2c3c1c1c(CO)cc(O)c4c1c1c5c(c(O)cc(O)c5c4=O)c4c(O)cc(O)c(c4c31)c2=O
Show InChI InChI=1S/C30H16O9/c1-7-2-9(32)19-23-15(7)16-8(6-31)3-10(33)20-24(16)28-26-18(12(35)5-14(37)22(26)30(20)39)17-11(34)4-13(36)21(29(19)38)25(17)27(23)28/h2-5,31-37H,6H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
1.90E+3n/an/an/an/an/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Mixed-type inhibition of rat liver cytosolic TrxR1 by Lineweaver-Burk plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin


(Homo sapiens)
BDBM50366237
PNG
(GAMBOGIC ACID)
Show SMILES CC(C)=CCC[C@@]1(C)Oc2c(CC=C(C)C)c3O[C@@]45[C@H]6C[C@@H](C=C4C(=O)c3c(O)c2C=C1)C(=O)[C@]5(C\C=C(\C)C(O)=O)OC6(C)C
Show InChI InChI=1S/C38H44O8/c1-20(2)10-9-15-36(8)16-14-24-29(39)28-30(40)26-18-23-19-27-35(6,7)46-37(33(23)41,17-13-22(5)34(42)43)38(26,27)45-32(28)25(31(24)44-36)12-11-21(3)4/h10-11,13-14,16,18,23,27,39H,9,12,15,17,19H2,1-8H3,(H,42,43)/b22-13-/t23-,27+,36-,37+,38-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
3.11E+3n/an/an/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant TRX-1 up to 60 mins by insulin reduction assay


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50333880
PNG
(CHEMBL1614664 | Hypericin | Pseudohypericin)
Show SMILES Cc1cc(O)c2c3c1c1c(CO)cc(O)c4c1c1c5c(c(O)cc(O)c5c4=O)c4c(O)cc(O)c(c4c31)c2=O
Show InChI InChI=1S/C30H16O9/c1-7-2-9(32)19-23-15(7)16-8(6-31)3-10(33)20-24(16)28-26-18(12(35)5-14(37)22(26)30(20)39)17-11(34)4-13(36)21(29(19)38)25(17)27(23)28/h2-5,31-37H,6H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
8.10E+3n/an/an/an/an/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Mixed-type inhibition of rat liver cytosolic TrxR1 at protein-substrate complex by Lineweaver-Burk plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50049873
PNG
(CHEMBL3322287)
Show SMILES NC(=O)c1c(no[n+]1[O-])C(=O)N1CC2N(CCc3ccccc23)C(=O)C1
Show InChI InChI=1/C16H15N5O5/c17-15(23)14-13(18-26-21(14)25)16(24)19-7-11-10-4-2-1-3-9(10)5-6-20(11)12(22)8-19/h1-4,11H,5-8H2,(H2,17,23)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Universit£ of Torino

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM35361
PNG
((5-oxidanidyl-4-thiophen-2-ylcarbonyl-1,2,5-oxadia...)
Show SMILES [O-]n1[o+]nc(C(=O)c2cccs2)c1C(=O)c1cccs1
Show InChI InChI=1S/C12H6N2O4S2/c15-11(7-3-1-5-19-7)9-10(14(17)18-13-9)12(16)8-4-2-6-20-8/h1-6H
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



National Human Genome Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni TGR


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50300734
PNG
(4-thienoyl-3-cyanofuroxan | CHEMBL576265)
Show SMILES [O-][n+]1onc(C(=O)c2cccs2)c1C#N
Show InChI InChI=1S/C8H3N3O3S/c9-4-5-7(10-14-11(5)13)8(12)6-2-1-3-15-6/h1-3H
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 63n/an/an/an/an/an/a



National Human Genome Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni TGR


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50049868
PNG
(CHEMBL3322292)
Show SMILES NC(=O)c1c(COc2ccc3CCN4C(CN(CC4=O)C(=O)C4CCCCC4)c3c2)no[n+]1[O-]
Show InChI InChI=1/C23H27N5O6/c24-22(30)21-18(25-34-28(21)32)13-33-16-7-6-14-8-9-27-19(17(14)10-16)11-26(12-20(27)29)23(31)15-4-2-1-3-5-15/h6-7,10,15,19H,1-5,8-9,11-13H2,(H2,24,30)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 83n/an/an/an/an/an/a



Universit£ of Torino

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin


(Homo sapiens)
BDBM50426066
PNG
(CHEMBL2315295)
Show SMILES [O-][N+](=O)c1ccc2nc(SSC3CCCCC3)[nH]c2c1
Show InChI InChI=1S/C13H15N3O2S2/c17-16(18)9-6-7-11-12(8-9)15-13(14-11)20-19-10-4-2-1-3-5-10/h6-8,10H,1-5H2,(H,14,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 90n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50300756
PNG
(3-formyl-4-phenyl-1,2,5-oxadiazole 2-oxide | CHEMB...)
Show SMILES [O-][n+]1onc(c1C=O)-c1ccccc1
Show InChI InChI=1S/C9H6N2O3/c12-6-8-9(10-14-11(8)13)7-4-2-1-3-5-7/h1-6H
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



National Human Genome Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni TGR


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50385274
PNG
(CHEMBL2035489)
Show SMILES COc1ccc2[se]n(CCn3[se]c4ccc(OC)cc4c3=O)c(=O)c2c1
Show InChI InChI=1S/C18H16N2O4Se2/c1-23-11-3-5-15-13(9-11)17(21)19(25-15)7-8-20-18(22)14-10-12(24-2)4-6-16(14)26-20/h3-6,9-10H,7-8H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50049874
PNG
(CHEMBL3322286)
Show SMILES COC(=O)c1c(no[n+]1[O-])C(=O)N1CC2N(CCc3ccccc23)C(=O)C1
Show InChI InChI=1/C17H16N4O6/c1-26-17(24)15-14(18-27-21(15)25)16(23)19-8-12-11-5-3-2-4-10(11)6-7-20(12)13(22)9-19/h2-5,12H,6-9H2,1H3
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 148n/an/an/an/an/an/a



Universit£ of Torino

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin


(Homo sapiens)
BDBM50426067
PNG
(CHEMBL2315297)
Show SMILES Fc1cc2[nH]c(SSC3CCCCC3)nc2cc1Cl
Show InChI InChI=1S/C13H14ClFN2S2/c14-9-6-11-12(7-10(9)15)17-13(16-11)19-18-8-4-2-1-3-5-8/h6-8H,1-5H2,(H,16,17)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 170n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin


(Homo sapiens)
BDBM50426065
PNG
(CHEMBL2315294)
Show SMILES O=C(c1ccccc1)c1ccc2nc(SSC3CCCCC3)[nH]c2c1
Show InChI InChI=1S/C20H20N2OS2/c23-19(14-7-3-1-4-8-14)15-11-12-17-18(13-15)22-20(21-17)25-24-16-9-5-2-6-10-16/h1,3-4,7-8,11-13,16H,2,5-6,9-10H2,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50385288
PNG
(CHEMBL2034987)
Show SMILES Fc1ccc2[se]n(CCn3[se]c4ccc(F)cc4c3=O)c(=O)c2c1
Show InChI InChI=1S/C16H10F2N2O2Se2/c17-9-1-3-13-11(7-9)15(21)19(23-13)5-6-20-16(22)12-8-10(18)2-4-14(12)24-20/h1-4,7-8H,5-6H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 280n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin


(Homo sapiens)
BDBM50426064
PNG
(CHEMBL2315292)
Show SMILES Nc1nc2nc(SSC3CCCCC3)[nH]c2c(=O)[nH]1
Show InChI InChI=1S/C11H15N5OS2/c12-10-14-8-7(9(17)16-10)13-11(15-8)19-18-6-4-2-1-3-5-6/h6H,1-5H2,(H4,12,13,14,15,16,17)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 290n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50049872
PNG
(CHEMBL3322288)
Show SMILES [O-][n+]1onc(C(=O)N2CC3N(CCc4ccccc34)C(=O)C2)c1C#N
Show InChI InChI=1/C16H13N5O4/c17-7-12-15(18-25-21(12)24)16(23)19-8-13-11-4-2-1-3-10(11)5-6-20(13)14(22)9-19/h1-4,13H,5-6,8-9H2
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 316n/an/an/an/an/an/a



Universit£ of Torino

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50385273
PNG
(CHEMBL2035491)
Show SMILES Oc1ccc2[se]n(CCn3[se]c4ccc(O)cc4c3=O)c(=O)c2c1
Show InChI InChI=1S/C16H12N2O4Se2/c19-9-1-3-13-11(7-9)15(21)17(23-13)5-6-18-16(22)12-8-10(20)2-4-14(12)24-18/h1-4,7-8,19-20H,5-6H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 320n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin


(Homo sapiens)
BDBM50426070
PNG
(CHEMBL2315306)
Show SMILES CCSSc1nc2ccccc2[nH]1
Show InChI InChI=1S/C9H10N2S2/c1-2-12-13-9-10-7-5-3-4-6-8(7)11-9/h3-6H,2H2,1H3,(H,10,11)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 340n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50385303
PNG
(CHEMBL2035460 | US8592468, EbSe14)
Show SMILES O=c1n(CCn2[se]c3ccccc3c2=O)[se]c2ccccc12
Show InChI InChI=1S/C16H12N2O2Se2/c19-15-11-5-1-3-7-13(11)21-17(15)9-10-18-16(20)12-6-2-4-8-14(12)22-18/h1-8H,9-10H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 350n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50049867
PNG
(CHEMBL3322293)
Show SMILES [O-][n+]1onc(COc2ccc3CCN4C(CN(CC4=O)C(=O)C4CCCCC4)c3c2)c1C#N
Show InChI InChI=1/C23H25N5O5/c24-11-20-19(25-33-28(20)31)14-32-17-7-6-15-8-9-27-21(18(15)10-17)12-26(13-22(27)29)23(30)16-4-2-1-3-5-16/h6-7,10,16,21H,1-5,8-9,12-14H2
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 350n/an/an/an/an/an/a



Universit£ of Torino

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 mins


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50300760
PNG
(4,4'-(thiophene-2,4-diyl)bis(3-cyano-1,2,5-oxadiaz...)
Show SMILES [O-]n1[o+]nc(-c2cc(cs2)-c2no[n+]([O-])c2C#N)c1C#N
Show InChI InChI=1S/C10H2N6O4S/c11-2-6-9(13-19-15(6)17)5-1-8(21-4-5)10-7(3-12)16(18)20-14-10/h1,4H
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 350n/an/an/an/an/an/a



National Human Genome Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni TGR


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50300761
PNG
(4,4'-(thiophene-2,5-diyl)bis(3-cyano-1,2,5-oxadiaz...)
Show SMILES [O-][n+]1onc(-c2ccc(s2)-c2no[n+]([O-])c2C#N)c1C#N
Show InChI InChI=1S/C10H2N6O4S/c11-3-5-9(13-19-15(5)17)7-1-2-8(21-7)10-6(4-12)16(18)20-14-10/h1-2H
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 400n/an/an/an/an/an/a



National Human Genome Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni TGR


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin


(Homo sapiens)
BDBM50426063
PNG
(CHEMBL2315290)
Show SMILES C1CCC(CC1)SSc1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C15H18N2S2/c1-3-7-12(8-4-1)14-11-16-15(17-14)19-18-13-9-5-2-6-10-13/h1,3-4,7-8,11,13H,2,5-6,9-10H2,(H,16,17)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 450n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50300762
PNG
(4,4'-(5-fluoro-1,3-phenylene)bis(3-cyano-1,2,5-oxa...)
Show SMILES [O-][n+]1onc(c1C#N)-c1cc(F)cc(c1)-c1no[n+]([O-])c1C#N
Show InChI InChI=1S/C12H3FN6O4/c13-8-2-6(11-9(4-14)18(20)22-16-11)1-7(3-8)12-10(5-15)19(21)23-17-12/h1-3H
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 480n/an/an/an/an/an/a



National Human Genome Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni TGR


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 2


(Plasmodium falciparum (isolate 3D7))
BDBM50182122
PNG
(CHEMBL204688 | bis(2,4-dinitrophenyl)sulfane)
Show SMILES [O-][N+](=O)c1ccc(Sc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C12H6N4O8S/c17-13(18)7-1-3-11(9(5-7)15(21)22)25-12-4-2-8(14(19)20)6-10(12)16(23)24/h1-6H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

AffyNet 
Article
PubMed
n/an/a 500n/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum TrxR


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin


(Homo sapiens)
BDBM50426068
PNG
(2-(Cyclohexyldisulfanyl)Benzo[D]Thiazole | CHEMBL2...)
Show SMILES C1CCC(CC1)SSc1nc2ccccc2s1
Show InChI InChI=1S/C13H15NS3/c1-2-6-10(7-3-1)16-17-13-14-11-8-4-5-9-12(11)15-13/h4-5,8-10H,1-3,6-7H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 510n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin


(Homo sapiens)
BDBM50426062
PNG
(CHEMBL2315288)
Show SMILES Nn1c(SSC2CCCCC2)nnc1-c1ccccc1
Show InChI InChI=1S/C14H18N4S2/c15-18-13(11-7-3-1-4-8-11)16-17-14(18)20-19-12-9-5-2-6-10-12/h1,3-4,7-8,12H,2,5-6,9-10,15H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 540n/an/an/an/an/an/a



Stanford University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant thioredoxin-mediated TG2 activation expressed in T84 cells assessed as blockade of 5-biotinamidopentylamine incorpora...


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50385279
PNG
(CHEMBL2035484)
Show SMILES [O-][N+](=O)c1ccc2[se]n(CCn3[se]c4ccc(cc4c3=O)[N+]([O-])=O)c(=O)c2c1
Show InChI InChI=1S/C16H10N4O6Se2/c21-15-11-7-9(19(23)24)1-3-13(11)27-17(15)5-6-18-16(22)12-8-10(20(25)26)2-4-14(12)28-18/h1-4,7-8H,5-6H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 570n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50300755
PNG
(3-carboxy-4-phenyl-1,2,5-oxadiazole 2-oxide | CHEM...)
Show SMILES OC(=O)c1c(no[n+]1[O-])-c1ccccc1
Show InChI InChI=1S/C9H6N2O4/c12-9(13)8-7(10-15-11(8)14)6-4-2-1-3-5-6/h1-5H,(H,12,13)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 630n/an/an/an/an/an/a



National Human Genome Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni TGR


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50385302
PNG
(CHEMBL2035461 | US8592468, EbSe15)
Show SMILES O=c1n(CCCn2[se]c3ccccc3c2=O)[se]c2ccccc12
Show InChI InChI=1S/C17H14N2O2Se2/c20-16-12-6-1-3-8-14(12)22-18(16)10-5-11-19-17(21)13-7-2-4-9-15(13)23-19/h1-4,6-9H,5,10-11H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 780n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50385278
PNG
(CHEMBL2035485)
Show SMILES Fc1ccc2c(c1)[se]n(CCn1[se]c3cc(F)ccc3c1=O)c2=O
Show InChI InChI=1S/C16H10F2N2O2Se2/c17-9-1-3-11-13(7-9)23-19(15(11)21)5-6-20-16(22)12-4-2-10(18)8-14(12)24-20/h1-4,7-8H,5-6H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 820n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50385287
PNG
(CHEMBL2035476)
Show SMILES Fc1ccc2[se]n(CCCn3[se]c4ccc(F)cc4c3=O)c(=O)c2c1
Show InChI InChI=1S/C17H12F2N2O2Se2/c18-10-2-4-14-12(8-10)16(22)20(24-14)6-1-7-21-17(23)13-9-11(19)3-5-15(13)25-21/h2-5,8-9H,1,6-7H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 860n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin glutathione reductase


(Schistosoma mansoni)
BDBM50300763
PNG
(4,4'-(1,4-phenylene)bis(3-cyano-1,2,5-oxadiazole 2...)
Show SMILES [O-][n+]1onc(c1C#N)-c1ccc(cc1)-c1no[n+]([O-])c1C#N
Show InChI InChI=1S/C12H4N6O4/c13-5-9-11(15-21-17(9)19)7-1-2-8(4-3-7)12-10(6-14)18(20)22-16-12/h1-4H
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



National Human Genome Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Schistosoma mansoni TGR


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50385301
PNG
(CHEMBL2035462)
Show SMILES O=c1n(CCCCn2[se]c3ccccc3c2=O)[se]c2ccccc12
Show InChI InChI=1S/C18H16N2O2Se2/c21-17-13-7-1-3-9-15(13)23-19(17)11-5-6-12-20-18(22)14-8-2-4-10-16(14)24-20/h1-4,7-10H,5-6,11-12H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.03E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay


Citation and Details
More data for this
Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic


(Rattus norvegicus)
BDBM50385292
PNG
(CHEMBL2035471)
Show SMILES Cc1ccc2[se]n(CCCn3[se]c4ccc(C)cc4c3=O)c(=O)c2c1
Show InChI InChI=1S/C19H18N2O2Se2/c1-12-4-6-16-14(10-12)18(22)20(24-16)8-3-9-21-19(23)15-11-13(2)5-7-17(15)25-21/h4-7,10-11H,3,8-9H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.16E+3n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of TrxR1 in rat liver homogenate preincubated for 5 mins measured by DNTB assay


Citation and Details
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 208 total )  |  Next  |  Last  >>
Jump to: