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Compile Data Set for Download or QSAR

Found 742 hits Enz. Inhib. hit(s) with Target = 'Zinc aminopeptidase'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497543
PNG
(CHEMBL3359693)
Show SMILES CC(C)(C)C(=O)NC(C(=O)NO)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C16H20N4O3/c1-16(2,3)15(22)18-13(14(21)19-23)11-5-7-12(8-6-11)20-10-4-9-17-20/h4-10,13,23H,1-3H3,(H,18,22)(H,19,21)
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0.700n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497544
PNG
(CHEMBL3359688)
Show SMILES CC(C)(C)OC(=O)NC(C(=O)NO)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C16H20N4O4/c1-16(2,3)24-15(22)18-13(14(21)19-23)11-5-7-12(8-6-11)20-10-4-9-17-20/h4-10,13,23H,1-3H3,(H,18,22)(H,19,21)
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0.800n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497553
PNG
(CHEMBL3359696)
Show SMILES ONC(=O)C(NC(=O)c1ccccc1F)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C18H15FN4O3/c19-15-5-2-1-4-14(15)17(24)21-16(18(25)22-26)12-6-8-13(9-7-12)23-11-3-10-20-23/h1-11,16,26H,(H,21,24)(H,22,25)
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1.90n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497545
PNG
(CHEMBL3359697)
Show SMILES ONC(=O)C(NC(=O)c1cccc(F)c1)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C18H15FN4O3/c19-14-4-1-3-13(11-14)17(24)21-16(18(25)22-26)12-5-7-15(8-6-12)23-10-2-9-20-23/h1-11,16,26H,(H,21,24)(H,22,25)
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4n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497556
PNG
(CHEMBL3359699)
Show SMILES Nc1cccc(c1)C(=O)NC(C(=O)NO)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C18H17N5O3/c19-14-4-1-3-13(11-14)17(24)21-16(18(25)22-26)12-5-7-15(8-6-12)23-10-2-9-20-23/h1-11,16,26H,19H2,(H,21,24)(H,22,25)
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5.5n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497551
PNG
(CHEMBL3359700)
Show SMILES Nc1ccc(cc1)C(=O)NC(C(=O)NO)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C18H17N5O3/c19-14-6-2-13(3-7-14)17(24)21-16(18(25)22-26)12-4-8-15(9-5-12)23-11-1-10-20-23/h1-11,16,26H,19H2,(H,21,24)(H,22,25)
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7.40n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497552
PNG
(CHEMBL3359698)
Show SMILES ONC(=O)C(NC(=O)c1ccc(F)cc1)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C18H15FN4O3/c19-14-6-2-13(3-7-14)17(24)21-16(18(25)22-26)12-4-8-15(9-5-12)23-11-1-10-20-23/h1-11,16,26H,(H,21,24)(H,22,25)
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11n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497557
PNG
(CHEMBL3359692)
Show SMILES CC(C)C(=O)NC(C(=O)NO)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C15H18N4O3/c1-10(2)14(20)17-13(15(21)18-22)11-4-6-12(7-5-11)19-9-3-8-16-19/h3-10,13,22H,1-2H3,(H,17,20)(H,18,21)
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12n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497547
PNG
(CHEMBL3359694)
Show SMILES CC(C)(C)NC(=O)NC(C(=O)NO)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C16H21N5O3/c1-16(2,3)19-15(23)18-13(14(22)20-24)11-5-7-12(8-6-11)21-10-4-9-17-21/h4-10,13,24H,1-3H3,(H,20,22)(H2,18,19,23)
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15n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497546
PNG
(CHEMBL3359695)
Show SMILES ONC(=O)C(NC(=O)c1ccccc1)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C18H16N4O3/c23-17(14-5-2-1-3-6-14)20-16(18(24)21-25)13-7-9-15(10-8-13)22-12-4-11-19-22/h1-12,16,25H,(H,20,23)(H,21,24)
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23n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497548
PNG
(CHEMBL3359691)
Show SMILES CCC(=O)NC(C(=O)NO)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C14H16N4O3/c1-2-12(19)16-13(14(20)17-21)10-4-6-11(7-5-10)18-9-3-8-15-18/h3-9,13,21H,2H2,1H3,(H,16,19)(H,17,20)
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41n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50339789
PNG
((S)-2-((2S,3R)-3-amino-2-hydroxy-4-(4-methoxypheny...)
Show SMILES COc1ccc(C[C@@H](N)[C@H](O)C(=O)N[C@@H](CC(C)C)C(O)=O)cc1
Show InChI InChI=1S/C17H26N2O5/c1-10(2)8-14(17(22)23)19-16(21)15(20)13(18)9-11-4-6-12(24-3)7-5-11/h4-7,10,13-15,20H,8-9,18H2,1-3H3,(H,19,21)(H,22,23)/t13-,14+,15+/m1/s1
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43n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-...


J Med Chem 54: 1655-66 (2011)


Article DOI: 10.1021/jm101227t
BindingDB Entry DOI: 10.7270/Q23X86ZX
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497554
PNG
(CHEMBL3359689)
Show SMILES Cl.NC(C(=O)NO)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C11H12N4O2.ClH/c12-10(11(16)14-17)8-2-4-9(5-3-8)15-7-1-6-13-15;/h1-7,10,17H,12H2,(H,14,16);1H
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75n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497549
PNG
(CHEMBL3359690)
Show SMILES CC(=O)NC(C(=O)NO)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C13H14N4O3/c1-9(18)15-12(13(19)16-20)10-3-5-11(6-4-10)17-8-2-7-14-17/h2-8,12,20H,1H3,(H,15,18)(H,16,19)
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113n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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190n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-...


J Med Chem 54: 1655-66 (2011)


Article DOI: 10.1021/jm101227t
BindingDB Entry DOI: 10.7270/Q23X86ZX
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50339790
PNG
((S)-2-((2S,3R)-3-amino-4-(4-(benzyloxy)phenyl)-2-h...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccc(OCc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C23H30N2O5/c1-15(2)12-20(23(28)29)25-22(27)21(26)19(24)13-16-8-10-18(11-9-16)30-14-17-6-4-3-5-7-17/h3-11,15,19-21,26H,12-14,24H2,1-2H3,(H,25,27)(H,28,29)/t19-,20+,21+/m1/s1
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490n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-...


J Med Chem 54: 1655-66 (2011)


Article DOI: 10.1021/jm101227t
BindingDB Entry DOI: 10.7270/Q23X86ZX
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497555
PNG
(CHEMBL3359686)
Show SMILES CC(C)(C)OC(=O)NC(C(O)=O)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C16H19N3O4/c1-16(2,3)23-15(22)18-13(14(20)21)11-5-7-12(8-6-11)19-10-4-9-17-19/h4-10,13H,1-3H3,(H,18,22)(H,20,21)
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>500n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50497550
PNG
(CHEMBL3359687)
Show SMILES Cl.NC(C(O)=O)c1ccc(cc1)-n1cccn1
Show InChI InChI=1S/C11H11N3O2.ClH/c12-10(11(15)16)8-2-4-9(5-3-8)14-7-1-6-13-14;/h1-7,10H,12H2,(H,15,16);1H
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>500n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum M1 incubated for 10 mins before H-Leu-NHMec substrate addition by fluorescence assay


J Med Chem 57: 9168-83 (2014)


Article DOI: 10.1021/jm501323a
BindingDB Entry DOI: 10.7270/Q2QN69RJ
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50339784
PNG
((S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamid...)
Show SMILES CCCC[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-2-3-9-13(16(21)22)18-15(20)14(19)12(17)10-11-7-5-4-6-8-11/h4-8,12-14,19H,2-3,9-10,17H2,1H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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900n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-...


J Med Chem 54: 1655-66 (2011)


Article DOI: 10.1021/jm101227t
BindingDB Entry DOI: 10.7270/Q23X86ZX
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50339785
PNG
((S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamid...)
Show SMILES N[C@H](Cc1ccccc1)[C@H](O)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C24H31N3O6/c25-19(15-17-9-3-1-4-10-17)21(28)22(29)27-20(23(30)31)13-7-8-14-26-24(32)33-16-18-11-5-2-6-12-18/h1-6,9-12,19-21,28H,7-8,13-16,25H2,(H,26,32)(H,27,29)(H,30,31)/t19-,20+,21+/m1/s1
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1.45E+3n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-...


J Med Chem 54: 1655-66 (2011)


Article DOI: 10.1021/jm101227t
BindingDB Entry DOI: 10.7270/Q23X86ZX
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50339791
PNG
((S)-2-((2S,3R)-3-amino-2-hydroxy-4-(naphthalen-2-y...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccc2ccccc2c1)C(O)=O
Show InChI InChI=1S/C20H26N2O4/c1-12(2)9-17(20(25)26)22-19(24)18(23)16(21)11-13-7-8-14-5-3-4-6-15(14)10-13/h3-8,10,12,16-18,23H,9,11,21H2,1-2H3,(H,22,24)(H,25,26)/t16-,17+,18+/m1/s1
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3.00E+3n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-...


J Med Chem 54: 1655-66 (2011)


Article DOI: 10.1021/jm101227t
BindingDB Entry DOI: 10.7270/Q23X86ZX
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50339792
PNG
((S)-2-((2S,3R)-3-amino-2-hydroxyheptanamido)-4-met...)
Show SMILES CCCC[C@@H](N)[C@H](O)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C13H26N2O4/c1-4-5-6-9(14)11(16)12(17)15-10(13(18)19)7-8(2)3/h8-11,16H,4-7,14H2,1-3H3,(H,15,17)(H,18,19)/t9-,10+,11+/m1/s1
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5.30E+3n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-...


J Med Chem 54: 1655-66 (2011)


Article DOI: 10.1021/jm101227t
BindingDB Entry DOI: 10.7270/Q23X86ZX
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50339786
PNG
((S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamid...)
Show SMILES N[C@H](Cc1ccccc1)[C@H](O)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C26H28N2O5/c27-22(15-18-7-3-1-4-8-18)24(29)25(30)28-23(26(31)32)16-19-11-13-21(14-12-19)33-17-20-9-5-2-6-10-20/h1-14,22-24,29H,15-17,27H2,(H,28,30)(H,31,32)/t22-,23+,24+/m1/s1
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>1.50E+4n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-...


J Med Chem 54: 1655-66 (2011)


Article DOI: 10.1021/jm101227t
BindingDB Entry DOI: 10.7270/Q23X86ZX
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50339787
PNG
((S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamid...)
Show SMILES N[C@H](Cc1ccccc1)[C@H](O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(O)=O
Show InChI InChI=1S/C23H24N2O4/c24-19(13-15-6-2-1-3-7-15)21(26)22(27)25-20(23(28)29)14-16-10-11-17-8-4-5-9-18(17)12-16/h1-12,19-21,26H,13-14,24H2,(H,25,27)(H,28,29)/t19-,20+,21+/m1/s1
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>1.50E+4n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-...


J Med Chem 54: 1655-66 (2011)


Article DOI: 10.1021/jm101227t
BindingDB Entry DOI: 10.7270/Q23X86ZX
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50339788
PNG
((S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamid...)
Show SMILES N[C@H](Cc1ccccc1)[C@H](O)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C25H26N2O4/c26-21(15-17-7-3-1-4-8-17)23(28)24(29)27-22(25(30)31)16-18-11-13-20(14-12-18)19-9-5-2-6-10-19/h1-14,21-23,28H,15-16,26H2,(H,27,29)(H,30,31)/t21-,22+,23+/m1/s1
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>1.50E+4n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum recombinant M1-aminopeptidase expressed in Escherichia coli after 40 mins uisng fluorigenic substrate L-Leucyl-7-...


J Med Chem 54: 1655-66 (2011)


Article DOI: 10.1021/jm101227t
BindingDB Entry DOI: 10.7270/Q23X86ZX
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206554
PNG
(CHEMBL219777 | N-(4-fluoro-benzyl)-N'-hydroxy-2-[1...)
Show SMILES ONC(=O)C(=C/c1ccccc1)\C(=O)NCc1ccc(F)cc1
Show InChI InChI=1S/C17H15FN2O3/c18-14-8-6-13(7-9-14)11-19-16(21)15(17(22)20-23)10-12-4-2-1-3-5-12/h1-10,23H,11H2,(H,19,21)(H,20,22)/b15-10-
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n/an/a 6n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206558
PNG
(CHEMBL375521 | N-hydroxy-N'-(4-phenyl-butyl)-2-[1-...)
Show SMILES ONC(=O)C(=C/c1ccccc1)\C(=O)NCCCCc1ccccc1
Show InChI InChI=1S/C20H22N2O3/c23-19(21-14-8-7-11-16-9-3-1-4-10-16)18(20(24)22-25)15-17-12-5-2-6-13-17/h1-6,9-10,12-13,15,25H,7-8,11,14H2,(H,21,23)(H,22,24)/b18-15-
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n/an/a 13n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206550
PNG
(2-benzyl-N-hydroxy-N'-(2-methyl-benzyl)-malonamide...)
Show SMILES Cc1ccccc1CNC(=O)C(Cc1ccccc1)C(=O)NO
Show InChI InChI=1S/C18H20N2O3/c1-13-7-5-6-10-15(13)12-19-17(21)16(18(22)20-23)11-14-8-3-2-4-9-14/h2-10,16,23H,11-12H2,1H3,(H,19,21)(H,20,22)
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n/an/a 41n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50197503
PNG
(CHEMBL425291 | N-hydroxy-2-isobutyl-N'-(3-phenoxy-...)
Show SMILES CC(C)CC(C(=O)NO)C(=O)NCc1cccc(Oc2ccccc2)c1
Show InChI InChI=1S/C20H24N2O4/c1-14(2)11-18(20(24)22-25)19(23)21-13-15-7-6-10-17(12-15)26-16-8-4-3-5-9-16/h3-10,12,14,18,25H,11,13H2,1-2H3,(H,21,23)(H,22,24)
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n/an/a 45n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50197497
PNG
(2-benzyl-N-hydroxy-N'-(4-phenyl-butyl)-malonamide ...)
Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCCCCc1ccccc1
Show InChI InChI=1S/C20H24N2O3/c23-19(21-14-8-7-11-16-9-3-1-4-10-16)18(20(24)22-25)15-17-12-5-2-6-13-17/h1-6,9-10,12-13,18,25H,7-8,11,14-15H2,(H,21,23)(H,22,24)
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n/an/a 46n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206556
PNG
(2-Benzyl-N-(4-fluoro-benzyl)-N'-hydroxy-malonamide...)
Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCc1ccc(F)cc1
Show InChI InChI=1S/C17H17FN2O3/c18-14-8-6-13(7-9-14)11-19-16(21)15(17(22)20-23)10-12-4-2-1-3-5-12/h1-9,15,23H,10-11H2,(H,19,21)(H,20,22)
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n/an/a 57n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206547
PNG
(CHEMBL374479 | N-hydroxy-2-isobutyl-N'-naphthalen-...)
Show SMILES CC(C)CC(C(=O)NO)C(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C18H22N2O3/c1-12(2)10-16(18(22)20-23)17(21)19-11-14-8-5-7-13-6-3-4-9-15(13)14/h3-9,12,16,23H,10-11H2,1-2H3,(H,19,21)(H,20,22)
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n/an/a 91n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206543
PNG
(2-benzyl-N-hydroxy-N'-naphthalen-1-ylmethyl-malona...)
Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C21H20N2O3/c24-20(19(21(25)23-26)13-15-7-2-1-3-8-15)22-14-17-11-6-10-16-9-4-5-12-18(16)17/h1-12,19,26H,13-14H2,(H,22,24)(H,23,25)
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n/an/a 107n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206551
PNG
(CHEMBL376198 | N-hydroxy-2-isobutyl-N'-(1,2,3,4-te...)
Show SMILES CC(C)CC(C(=O)NO)C(=O)N1CCCc2ccccc12
Show InChI InChI=1S/C16H22N2O3/c1-11(2)10-13(15(19)17-21)16(20)18-9-5-7-12-6-3-4-8-14(12)18/h3-4,6,8,11,13,21H,5,7,9-10H2,1-2H3,(H,17,19)
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n/an/a 109n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50062453
PNG
(2-Benzyl-N-hydroxy-N'-(3-phenyl-propyl)-malonamide...)
Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCCCc1ccccc1
Show InChI InChI=1S/C19H22N2O3/c22-18(20-13-7-12-15-8-3-1-4-9-15)17(19(23)21-24)14-16-10-5-2-6-11-16/h1-6,8-11,17,24H,7,12-14H2,(H,20,22)(H,21,23)
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n/an/a 125n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50062474
PNG
(2,N-Dibenzyl-N'-hydroxy-malonamide | 2N-dibenzyl-N...)
Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCc1ccccc1
Show InChI InChI=1S/C17H18N2O3/c20-16(18-12-14-9-5-2-6-10-14)15(17(21)19-22)11-13-7-3-1-4-8-13/h1-10,15,22H,11-12H2,(H,18,20)(H,19,21)
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n/an/a 125n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206552
PNG
(2-(3-phenoxybenzyl)-N1-(4-chlorobenzyl)-N3-hydroxy...)
Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)NCc1ccc(Cl)cc1
Show InChI InChI=1S/C23H21ClN2O4/c24-18-11-9-16(10-12-18)15-25-22(27)21(23(28)26-29)14-17-5-4-8-20(13-17)30-19-6-2-1-3-7-19/h1-13,21,29H,14-15H2,(H,25,27)(H,26,28)
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n/an/a 130n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50197501
PNG
(2-(3-phenoxybenzyl)-N1-benzyl-N3-hydroxymalonamide...)
Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)NCc1ccccc1
Show InChI InChI=1S/C23H22N2O4/c26-22(24-16-17-8-3-1-4-9-17)21(23(27)25-28)15-18-10-7-13-20(14-18)29-19-11-5-2-6-12-19/h1-14,21,28H,15-16H2,(H,24,26)(H,25,27)
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n/an/a 164n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206546
PNG
(2-benzyl-N-(4-chloro-benzyl)-N'-hydroxy-malonamide...)
Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCc1ccc(Cl)cc1
Show InChI InChI=1S/C17H17ClN2O3/c18-14-8-6-13(7-9-14)11-19-16(21)15(17(22)20-23)10-12-4-2-1-3-5-12/h1-9,15,23H,10-11H2,(H,19,21)(H,20,22)
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n/an/a 170n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206557
PNG
(2-benzyl-3-(4-benzyl-piperidin-1-yl)-N-hydroxy-3-o...)
Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H26N2O3/c25-21(23-27)20(16-18-9-5-2-6-10-18)22(26)24-13-11-19(12-14-24)15-17-7-3-1-4-8-17/h1-10,19-20,27H,11-16H2,(H,23,25)
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n/an/a 206n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50197505
PNG
(2-(3-phenoxybenzyl)-N1-hydroxy-N3-(4-phenylbutyl)m...)
Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)NCCCCc1ccccc1
Show InChI InChI=1S/C26H28N2O4/c29-25(27-17-8-7-12-20-10-3-1-4-11-20)24(26(30)28-31)19-21-13-9-16-23(18-21)32-22-14-5-2-6-15-22/h1-6,9-11,13-16,18,24,31H,7-8,12,17,19H2,(H,27,29)(H,28,30)
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n/an/a 225n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206566
PNG
(2-(3-phenoxybenzyl)-N1-(4-(trifluoromethyl)benzyl)...)
Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C24H21F3N2O4/c25-24(26,27)18-11-9-16(10-12-18)15-28-22(30)21(23(31)29-32)14-17-5-4-8-20(13-17)33-19-6-2-1-3-7-19/h1-13,21,32H,14-15H2,(H,28,30)(H,29,31)
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n/an/a 231n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206564
PNG
(2-(3-phenoxybenzyl)-3-(4-benzylpiperidin-1-yl)-N-h...)
Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C28H30N2O4/c31-27(29-33)26(20-23-10-7-13-25(19-23)34-24-11-5-2-6-12-24)28(32)30-16-14-22(15-17-30)18-21-8-3-1-4-9-21/h1-13,19,22,26,33H,14-18,20H2,(H,29,31)
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n/an/a 248n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206545
PNG
(2-benzyl-3-(3,4-dihydro-1H-isoquinolin-2-yl)-N-hyd...)
Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)N1CCc2ccccc2C1
Show InChI InChI=1S/C19H20N2O3/c22-18(20-24)17(12-14-6-2-1-3-7-14)19(23)21-11-10-15-8-4-5-9-16(15)13-21/h1-9,17,24H,10-13H2,(H,20,22)
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n/an/a 253n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
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n/an/a 284n/an/an/an/an/an/a



Universit£ de Lille 2

Curated by ChEMBL


Assay Description
Inhibitory activity for Plasmodium falciparum Zinc aminopeptidase


Bioorg Med Chem Lett 13: 2659-62 (2003)


Article DOI: 10.1016/s0960-894x(03)00550-x
BindingDB Entry DOI: 10.7270/Q20G3KPK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206555
PNG
(2-[1-Phenyl-meth-(Z)-ylidene]-malonic Acid Monoeth...)
Show SMILES ONC(=O)C(=C\c1ccccc1)\C(=O)NCc1ccc(F)cc1
Show InChI InChI=1S/C17H15FN2O3/c18-14-8-6-13(7-9-14)11-19-16(21)15(17(22)20-23)10-12-4-2-1-3-5-12/h1-10,23H,11H2,(H,19,21)(H,20,22)/b15-10+
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n/an/a 330n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50197495
PNG
(2-(4-benzyl-piperidine-1-carbonyl)-4-methyl-pentan...)
Show SMILES CC(C)CC(C(=O)NO)C(=O)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H28N2O3/c1-14(2)12-17(18(22)20-24)19(23)21-10-8-16(9-11-21)13-15-6-4-3-5-7-15/h3-7,14,16-17,24H,8-13H2,1-2H3,(H,20,22)
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n/an/a 406n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50197494
PNG
(CHEMBL220253 | N-benzyl-N'-hydroxy-2-isobutyl-malo...)
Show SMILES CC(C)CC(C(=O)NO)C(=O)NCc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c1-10(2)8-12(14(18)16-19)13(17)15-9-11-6-4-3-5-7-11/h3-7,10,12,19H,8-9H2,1-2H3,(H,15,17)(H,16,18)
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n/an/a 495n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50206565
PNG
(2-(3-phenoxybenzyl)-N1-hydroxy-N3-(3-phenylpropyl)...)
Show SMILES ONC(=O)C(Cc1cccc(Oc2ccccc2)c1)C(=O)NCCCc1ccccc1
Show InChI InChI=1S/C25H26N2O4/c28-24(26-16-8-12-19-9-3-1-4-10-19)23(25(29)27-30)18-20-11-7-15-22(17-20)31-21-13-5-2-6-14-21/h1-7,9-11,13-15,17,23,30H,8,12,16,18H2,(H,26,28)(H,27,29)
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n/an/a 527n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
Zinc aminopeptidase


(Plasmodium falciparum (isolate FcB1 / Columbia))
BDBM50062478
PNG
(CHEMBL116641 | N-Hydroxy-2-isobutyl-N'-(3-phenyl-p...)
Show SMILES CC(C)CC(C(=O)NO)C(=O)NCCCc1ccccc1
Show InChI InChI=1S/C16H24N2O3/c1-12(2)11-14(16(20)18-21)15(19)17-10-6-9-13-7-4-3-5-8-13/h3-5,7-8,12,14,21H,6,9-11H2,1-2H3,(H,17,19)(H,18,20)
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n/an/a 790n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase


J Med Chem 50: 1322-34 (2007)


Article DOI: 10.1021/jm061169b
BindingDB Entry DOI: 10.7270/Q2M908B3
More data for this
Ligand-Target Pair
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