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Found 176 Enz. Inhib. hit(s) with all data for entry = 9144
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM444986(US10668167, Compound 3)
Affinity DataIC50:  2.60nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445033(US10668167, Compound 41)
Affinity DataIC50:  2.80nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445027(US10668167, Compound 35)
Affinity DataIC50:  3.40nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445028(US10668167, Compound 36)
Affinity DataIC50:  3.40nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM444986(US10668167, Compound 3)
Affinity DataIC50:  3.60nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445051(US10668167, Compound 63)
Affinity DataIC50:  3.80nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445041(US10668167, Compound 51)
Affinity DataIC50:  4.20nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445039(US10668167, Compound 49)
Affinity DataIC50:  5.60nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445045(US10668167, Compound 57)
Affinity DataIC50:  6.30nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445042(US10668167, Compound 53)
Affinity DataIC50:  6.5nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445037(US10668167, Compound 47)
Affinity DataIC50:  6.5nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM444985(US10668167, Compound 2)
Affinity DataIC50:  6.60nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445027(US10668167, Compound 35)
Affinity DataIC50:  6.70nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445012(US10668167, Compound 21)
Affinity DataIC50:  7.30nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445024(US10668167, Compound 32)
Affinity DataIC50:  7.40nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445053(US10668167, Compound 67)
Affinity DataIC50:  7.49nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445046(US10668167, Compound 58)
Affinity DataIC50:  7.80nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445040(US10668167, Compound 50)
Affinity DataIC50:  8nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445013(US10668167, Compound 22)
Affinity DataIC50:  8.20nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445011(US10668167, Compound 20)
Affinity DataIC50:  8.60nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445015(US10668167, Compound 24)
Affinity DataIC50:  8.90nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445012(US10668167, Compound 21)
Affinity DataIC50:  9.40nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445000(US10668167, Compound 9)
Affinity DataIC50:  9.40nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445043(US10668167, Compound 54)
Affinity DataIC50:  9.5nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM444988(US10668167, Compound 4)
Affinity DataIC50:  9.5nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445054(US10668167, Compound 69)
Affinity DataIC50:  9.60nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445010(US10668167, Compound 19)
Affinity DataIC50:  10.1nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445018(US10668167, Compound 27)
Affinity DataIC50:  10.2nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445001(US10668167, Compound 10)
Affinity DataIC50:  10.5nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445023(US10668167, Compound 31)
Affinity DataIC50:  10.7nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445014(US10668167, Compound 23)
Affinity DataIC50:  10.8nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445032(US10668167, Compound 40)
Affinity DataIC50:  11.1nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445044(US10668167, Compound 55)
Affinity DataIC50:  11.4nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445000(US10668167, Compound 9)
Affinity DataIC50:  11.6nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445052(US10668167, Compound 64)
Affinity DataIC50:  11.6nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445038(US10668167, Compound 48)
Affinity DataIC50:  11.8nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM444995(US10668167, Compound 5)
Affinity DataIC50:  12nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445054(US10668167, Compound 69)
Affinity DataIC50:  12nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445048(US10668167, Compound 60)
Affinity DataIC50:  12.1nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445026(US10668167, Compound 34)
Affinity DataIC50:  12.2nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445034(US10668167, Compound 42)
Affinity DataIC50:  12.4nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445047(US10668167, Compound 59)
Affinity DataIC50:  12.7nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445030(US10668167, Compound 38)
Affinity DataIC50:  12.8nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445024(US10668167, Compound 32)
Affinity DataIC50:  13nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445029(US10668167, Compound 37)
Affinity DataIC50:  13.1nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445021(US10668167, Compound 29)
Affinity DataIC50:  13.2nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445016(US10668167, Compound 25)
Affinity DataIC50:  13.3nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445047(US10668167, Compound 59)
Affinity DataIC50:  13.4nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445041(US10668167, Compound 51)
Affinity DataIC50:  13.6nMAssay Description:Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM445015(US10668167, Compound 24)
Affinity DataIC50:  13.8nMAssay Description:Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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