Compile Data Set for Download or QSAR
maximum 50k data
Found 51 Enz. Inhib. hit(s) with all data for entry = 9258
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453395(US10730830, Example 51 (2))
Affinity DataIC50:  50nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453382(4-(6-{2-[4-(Trifluoromethyl)phenoxy]ethoxy}-1,2,4,...)
Affinity DataIC50:  50nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453386(US10730830, Example 18 (18))
Affinity DataIC50:  50nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453388(4-{6-[(5-Phenylpentyl)oxy]-1,2,4,5-tetrahydro-3H-3...)
Affinity DataIC50:  50nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453390(1-[8-(3-Phenylpropoxy)-1,2,3,4-tetrahydro-2-naphth...)
Affinity DataIC50:  50nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453391(3-{6-[2-(1-Naphthyl)ethoxy]-1,2,4,5-tetrahydro-3H-...)
Affinity DataIC50:  50nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453392(4-[7-Methyl-6-(3-phenylpropoxy)-1,2,4,5-tetrahydro...)
Affinity DataIC50:  50nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453394((−)-1-{8-[2-(1-Naphthyl)ethoxy]-1,2,3,4-tetr...)
Affinity DataIC50:  50nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453397(US10730830, Example 48)
Affinity DataIC50:  550nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453396(US10730830, Example 37)
Affinity DataIC50:  550nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453384(4-[6-(3-Cyclohexylpropoxy)-1,2,4,5-tetrahydro-3H-3...)
Affinity DataIC50:  550nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453398(4-[6-(Octyloxy)-1,2,4,5-tetrahydro-3H-3-benzazepin...)
Affinity DataIC50:  550nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453389(4-{6-[2-(Bicyclo[4.2.0]octa-1,3,5-trien-7-yl)ethox...)
Affinity DataIC50:  550nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453379(3-[6-({(2E)-3-[4-(Trifluoromethyl)phenyl]-2-propen...)
Affinity DataIC50:  550nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453387(4-[6-(2-Phenylethoxy)-1,2,4,5-tetrahydro-3H-3-benz...)
Affinity DataIC50:  550nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453385(4-[6-(1,2,3,4-Tetrahydro-2-naphthalenylmethoxy)-1,...)
Affinity DataIC50:  550nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453383(US10730830, Example 3 (3) | rel-(1R,2R)-2-{[6-({(2...)
Affinity DataIC50:  550nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453399(4-{6-[3-(tetrahydro-2H-pyran-4-yl)propoxy]-1,2,4,5...)
Affinity DataIC50:  550nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453376(4-[5-{[(2E)-3-(4-Isopropylphenyl)-2-propen-1-yl]ox...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453381(1-[5-({(2E)-3-[4-(Trifluoromethyl)phenyl]-2-propen...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453322(4-{5-[2-(2-naphthyl)ethoxy]-3,4-dihydro-2(1H)-isoq...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453377(4-[5-({(2E)-3-[4-(Difluoromethoxy)phenyl]-2-propen...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453375(4-[8-({(2E)-3-[4-(Trifluoromethyl)phenyl]-2-propen...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453380(US10730830, Example 49)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453394((−)-1-{8-[2-(1-Naphthyl)ethoxy]-1,2,3,4-tetr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453392(4-[7-Methyl-6-(3-phenylpropoxy)-1,2,4,5-tetrahydro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453391(3-{6-[2-(1-Naphthyl)ethoxy]-1,2,4,5-tetrahydro-3H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453390(1-[8-(3-Phenylpropoxy)-1,2,3,4-tetrahydro-2-naphth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453389(4-{6-[2-(Bicyclo[4.2.0]octa-1,3,5-trien-7-yl)ethox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453388(4-{6-[(5-Phenylpentyl)oxy]-1,2,4,5-tetrahydro-3H-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453387(4-[6-(2-Phenylethoxy)-1,2,4,5-tetrahydro-3H-3-benz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453386(US10730830, Example 18 (18))
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453385(4-[6-(1,2,3,4-Tetrahydro-2-naphthalenylmethoxy)-1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453384(4-[6-(3-Cyclohexylpropoxy)-1,2,4,5-tetrahydro-3H-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453399(4-{6-[3-(tetrahydro-2H-pyran-4-yl)propoxy]-1,2,4,5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453382(4-(6-{2-[4-(Trifluoromethyl)phenoxy]ethoxy}-1,2,4,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453379(3-[6-({(2E)-3-[4-(Trifluoromethyl)phenyl]-2-propen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453396(US10730830, Example 37)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453395(US10730830, Example 51 (2))
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453398(4-[6-(Octyloxy)-1,2,4,5-tetrahydro-3H-3-benzazepin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453397(US10730830, Example 48)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453383(US10730830, Example 3 (3) | rel-(1R,2R)-2-{[6-({(2...)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453381(1-[5-({(2E)-3-[4-(Trifluoromethyl)phenyl]-2-propen...)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453380(US10730830, Example 49)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453377(4-[5-({(2E)-3-[4-(Difluoromethoxy)phenyl]-2-propen...)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453376(4-[5-{[(2E)-3-(4-Isopropylphenyl)-2-propen-1-yl]ox...)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453375(4-[8-({(2E)-3-[4-(Trifluoromethyl)phenyl]-2-propen...)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453322(4-{5-[2-(2-naphthyl)ethoxy]-3,4-dihydro-2(1H)-isoq...)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound of the Present Invention on Binding of [33P]-S1P to S1P5 (EDG-8)A reaction was carried out in a 96-well microplate by using membrane fractio...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453400(4-[6-(3-Phenylpropoxy)-1,2,4,5-tetrahydro-3H-3-ben...)
Affinity DataEC50:  50nMAssay Description:CHO cells which were made to overexpress human S1P5 (EDG-8) gene were cultured in Ham's F12 Medium (manufactured by Gibco-BRL) containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM453386(US10730830, Example 18 (18))
Affinity DataEC50:  50nMAssay Description:CHO cells which were made to overexpress human S1P5 (EDG-8) gene were cultured in Ham's F12 Medium (manufactured by Gibco-BRL) containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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