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Found 29 Enz. Inhib. hit(s) with all data for entry = 10022
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM50051590(CHEMBL3337524 | US11071729, Compound 1)
Affinity DataEC50:  295nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508890(US11071729, Compound 29)
Affinity DataEC50:  132nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508864(US11071729, Compound 3)
Affinity DataEC50:  132nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM50051591(CHEMBL3337525 | US11071729, Compound 4)
Affinity DataEC50:  355nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508866(US11071729, Compound 5)
Affinity DataEC50:  126nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508867(US11071729, Compound 6)
Affinity DataEC50:  457nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508868(US11071729, Compound 7)
Affinity DataEC50:  240nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508869(US11071729, Compound 8)
Affinity DataEC50:  912nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508870(US11071729, Compound 9)
Affinity DataEC50:  269nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508871(US11071729, Compound 10)
Affinity DataEC50:  132nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508872(US11071729, Compound 11)
Affinity DataEC50:  77.6nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508873(US11071729, Compound 12)
Affinity DataEC50:  93.3nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508874(US11071729, Compound 13)
Affinity DataEC50:  229nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508875(US11071729, Compound 14)
Affinity DataEC50:  120nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508876(US11071729, Compound 15)
Affinity DataEC50:  100nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508877(US11071729, Compound 16)
Affinity DataEC50:  75.9nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508878(US11071729, Compound 17)
Affinity DataEC50:  269nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508879(US11071729, Compound 18)
Affinity DataEC50:  63.1nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM50051607(CHEMBL3337526 | US11071729, Compound 19)
Affinity DataEC50:  195nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508881(US11071729, Compound 20)
Affinity DataEC50:  123nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508882(US11071729, Compound 21)
Affinity DataEC50:  562nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508883(US11071729, Compound 22)
Affinity DataEC50:  891nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508884(US11071729, Compound 23)
Affinity DataEC50:  263nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508885(US11071729, Compound 24)
Affinity DataEC50:  123nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508886(US11071729, Compound 25)
Affinity DataEC50:  148nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM509561(US11071729, Compound 26)
Affinity DataEC50:  389nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508888(US11071729, Compound 27)
Affinity DataEC50:  347nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM508889(US11071729, Compound 28)
Affinity DataEC50:  87.1nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Addex Pharmaceuticals

US Patent
LigandPNGBDBM50051408(CHEMBL3337527 | US11071729, Compound 2)
Affinity DataEC50:  182nMAssay Description:Measurement of mGluR2 positive allosteric modulatory activity of test compounds in membranes containing human mGluR2 was performed using frozen membr...More data for this Ligand-Target Pair