Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with all data for entry = 5936
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM3737(US8530670, 18)
Affinity DataKi:  4.40nM ΔG°:  -48.5kJ/mole IC50:  235nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM3740(US8530670, 27)
Affinity DataKi:  4.60nM ΔG°:  -48.4kJ/mole IC50:  46.1nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM3742(US8530670, 4)
Affinity DataKi:  11.9nM ΔG°:  -46.0kJ/mole IC50:  73.1nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM3914(US8530670, 3)
Affinity DataKi:  13.9nM ΔG°:  -45.6kJ/mole IC50:  72.5nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM101438(US8530670, 15 | US8530670, 2)
Affinity DataKi:  18.8nM ΔG°:  -44.8kJ/mole IC50:  85.8nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent