Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 6602
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50040237(2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)
Affinity DataKi:  0.490nMAssay Description:The ability of test compounds to displace 3H-raclopride at the D2s receptor can be determined on membranes from D2s-transfected CHO cells (Bmax 13 pm...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141314(US8653257, 2-Chloro-11-piperazin-1-yl-dibenzo[b,f]...)
Affinity DataKi:  0.700nMAssay Description:The ability of test compounds to displace 3H-raclopride at the D2s receptor can be determined on membranes from D2s-transfected CHO cells (Bmax 13 pm...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141315(US8653257, 2-Fluoro-11-(4-methyl-piperazin-1-yl)-d...)
Affinity DataKi:  1.10nMAssay Description:The ability of test compounds to displace 3H-raclopride at the D2s receptor can be determined on membranes from D2s-transfected CHO cells (Bmax 13 pm...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141312(US8653257, 2-Fluoro-11-piperazin-1-yl-dibenzo[b,f]...)
Affinity DataKi:  11nMAssay Description:The ability of test compounds to displace 3H-raclopride at the D2s receptor can be determined on membranes from D2s-transfected CHO cells (Bmax 13 pm...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM141313(US8653257, 11-Piperazin-1-yl-dibenzo[b,f][1,4]thia...)
Affinity DataKi:  37nMAssay Description:The ability of test compounds to displace 3H-raclopride at the D2s receptor can be determined on membranes from D2s-transfected CHO cells (Bmax 13 pm...More data for this Ligand-Target Pair
In DepthDetails US Patent