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Found 12 Enz. Inhib. hit(s) with all data for entry = 6282
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120365(US8703807, 1)
Affinity DataIC50:  7.70nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120375(US8703807, 11)
Affinity DataIC50:  10nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120371(US8703807, 7)
Affinity DataIC50:  13.7nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120369(US8703807, 5)
Affinity DataIC50:  16.3nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120368(US8703807, 4)
Affinity DataIC50:  27.4nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120373(US8703807, 9)
Affinity DataIC50:  30.6nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120376(US8703807, 12)
Affinity DataIC50:  37nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120374(US8703807, 10)
Affinity DataIC50:  41.8nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120367(US8703807, 3)
Affinity DataIC50:  50.9nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120366(US8703807, 2)
Affinity DataIC50:  68.1nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120372(US8703807, 8)
Affinity DataIC50:  213nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM120370(US8703807, 6)
Affinity DataIC50:  264nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent