Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 6319
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123054(US8742134, (1))
Affinity DataKi:  0.160nM ΔG°:  -55.3kJ/mole IC50:  0.230nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123055(US8742134, (2) | US8742134, (7))
Affinity DataKi:  0.180nM ΔG°:  -55.1kJ/mole IC50:  0.25nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123056(US8742134, (3) | US8742134, (8))
Affinity DataKi:  0.180nM ΔG°:  -55.1kJ/mole IC50:  0.25nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123057(US8742134, (4) | US8742134, (5) | US8742134, (6))
Affinity DataKi:  0.220nM ΔG°:  -54.6kJ/mole IC50:  0.300nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123057(US8742134, (4) | US8742134, (5) | US8742134, (6))
Affinity DataKi:  1.5nM ΔG°:  -49.9kJ/mole IC50:  2.10nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123057(US8742134, (4) | US8742134, (5) | US8742134, (6))
Affinity DataKi:  2.10nM ΔG°:  -49.0kJ/mole IC50:  2.90nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123055(US8742134, (2) | US8742134, (7))
Affinity DataKi:  14nM ΔG°:  -44.4kJ/mole IC50:  19nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theron Pharmaceuticals

US Patent
LigandPNGBDBM123056(US8742134, (3) | US8742134, (8))
Affinity DataKi:  26nM ΔG°:  -42.9kJ/mole IC50:  36nMT: 2°CAssay Description:Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...More data for this Ligand-Target Pair
In DepthDetails US Patent