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Found 9 Enz. Inhib. hit(s) with all data for entry = 6427
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Institute Of Cancer Research

US Patent
LigandPNGBDBM50307959(4-(4-Chlorobenzyl)-1-(1H-pyrrolo[2,3-b]pyridin-4-y...)
Affinity DataIC50: <10nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Institute Of Cancer Research

US Patent
LigandPNGBDBM128294(US8796293, 30)
Affinity DataIC50: <30nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Institute Of Cancer Research

US Patent
LigandPNGBDBM50307955(4-(2,4-Dichlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50: <30nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Institute Of Cancer Research

US Patent
LigandPNGBDBM128293(US8796293, 14)
Affinity DataIC50: <100nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Institute Of Cancer Research

US Patent
LigandPNGBDBM50307942(4-Amino-N-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  143nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Institute Of Cancer Research

US Patent
LigandPNGBDBM50237622(4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: <1.00E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Institute Of Cancer Research

US Patent
LigandPNGBDBM50307981(4-(2-Chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: >1.00E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Institute Of Cancer Research

US Patent
LigandPNGBDBM128292(US8796293, 4)
Affinity DataIC50: >1.00E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Institute Of Cancer Research

US Patent
LigandPNGBDBM50307943(4-(4-tert-Butylbenzyl)-1-(7H-pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  2.70E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In DepthDetails US Patent