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Found 100 Enz. Inhib. hit(s) with all data for entry = 6463
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130419(US8822505, 21 | US8822505, 23 | US8822505, 24)
Affinity DataIC50:  0.377nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130420(US8822505, 22 | US8822505, 25 | US8822505, 26)
Affinity DataIC50:  0.492nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130414(US8822505, 14 | US8822505, 16)
Affinity DataIC50:  0.525nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130414(US8822505, 14 | US8822505, 16)
Affinity DataIC50:  0.613nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130408(US8822505, 8)
Affinity DataIC50:  0.694nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130415(US8822505, 15)
Affinity DataIC50:  0.721nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130409(US8822505, 9)
Affinity DataIC50:  0.779nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130445(US8822505, 47)
Affinity DataIC50:  0.791nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130448(US8822505, 50)
Affinity DataIC50:  0.900nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130443(US8822505, 45)
Affinity DataIC50:  0.965nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130447(US8822505, 49)
Affinity DataIC50:  1nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130450(US8822505, 52)
Affinity DataIC50:  1nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130419(US8822505, 21 | US8822505, 23 | US8822505, 24)
Affinity DataIC50:  1.04nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130412(US8822505, 12)
Affinity DataIC50:  1.07nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130425(US8822505, 27 | US8822505, 28)
Affinity DataIC50:  1.08nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130413(US8822505, 13)
Affinity DataIC50:  1.09nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130444(US8822505, 46)
Affinity DataIC50:  1.12nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130403(US8822505, 3)
Affinity DataIC50:  1.20nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130420(US8822505, 22 | US8822505, 25 | US8822505, 26)
Affinity DataIC50:  1.26nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130410(US8822505, 10)
Affinity DataIC50:  1.26nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130411(US8822505, 11)
Affinity DataIC50:  1.27nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130429(US8822505, 31 | US8822505, 35)
Affinity DataIC50:  1.30nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130430(US8822505, 32 | US8822505, 36)
Affinity DataIC50:  1.42nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130402(US8822505, 2)
Affinity DataIC50:  1.49nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130439(US8822505, 41)
Affinity DataIC50:  1.55nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130429(US8822505, 31 | US8822505, 35)
Affinity DataIC50:  1.57nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130417(US8822505, 19)
Affinity DataIC50:  1.67nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130430(US8822505, 32 | US8822505, 36)
Affinity DataIC50:  1.77nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130446(US8822505, 48)
Affinity DataIC50:  1.85nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130449(US8822505, 51)
Affinity DataIC50:  2nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130442(US8822505, 44)
Affinity DataIC50:  2.08nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130438(US8822505, 40)
Affinity DataIC50:  2.13nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130427(US8822505, 29 | US8822505, 30)
Affinity DataIC50:  2.22nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130441(US8822505, 43)
Affinity DataIC50:  2.33nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130404(US8822505, 4)
Affinity DataIC50:  2.75nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130418(US8822505, 20)
Affinity DataIC50:  2.92nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130406(US8822505, 6)
Affinity DataIC50:  3.16nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130401(US8822505, 1)
Affinity DataIC50:  3.22nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130432(US8822505, 34)
Affinity DataIC50:  3.48nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130431(US8822505, 33)
Affinity DataIC50:  3.54nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130405(US8822505, 5)
Affinity DataIC50:  3.69nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130407(US8822505, 7)
Affinity DataIC50:  3.82nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130435(US8822505, 37 | US8822505, 38)
Affinity DataIC50:  3.83nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130435(US8822505, 37 | US8822505, 38)
Affinity DataIC50:  4.16nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130420(US8822505, 22 | US8822505, 25 | US8822505, 26)
Affinity DataIC50:  4.45nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130419(US8822505, 21 | US8822505, 23 | US8822505, 24)
Affinity DataIC50:  4.56nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130440(US8822505, 42)
Affinity DataIC50:  4.60nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130413(US8822505, 13)
Affinity DataIC50:  4.60nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130447(US8822505, 49)
Affinity DataIC50:  5nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM130448(US8822505, 50)
Affinity DataIC50:  5nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
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