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Found 82 Enz. Inhib. hit(s) with all data for entry = 6486
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50448761(CHEMBL3128021 | US8835445, 22)
Affinity DataKi:  0.00200nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131853(US8835445, 36)
Affinity DataKi:  0.00500nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50448757(CHEMBL3128025 | US8835445, 18)
Affinity DataKi:  0.00500nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50448759(CHEMBL3128023 | US8835445, 17)
Affinity DataKi:  0.00700nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50448744(CHEMBL3128014 | US8835445, 25 | US8835445, 34)
Affinity DataKi:  0.0110nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131845(US8835445, 23)
Affinity DataKi:  0.0110nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50448756(CHEMBL3128026 | US8835445, 21)
Affinity DataKi:  0.0120nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50448744(CHEMBL3128014 | US8835445, 25 | US8835445, 34)
Affinity DataKi:  0.0160nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131846(US8835445, 24)
Affinity DataKi:  0.0190nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50351175(CHEMBL1818127 | US8835445, 30)
Affinity DataKi:  0.0200nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131850(US8835445, 32)
Affinity DataKi:  0.0210nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50448753(CHEMBL3127912 | US8835445, 16)
Affinity DataKi:  0.0220nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50351173(CHEMBL1818129 | US8835445, 40)
Affinity DataKi:  0.0250nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50351174(CHEMBL1818128 | US8835445, 31)
Affinity DataKi:  0.0260nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50448745(CHEMBL3128013 | US8835445, 26)
Affinity DataKi:  0.0300nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131854(US8835445, 37)
Affinity DataKi:  0.0390nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131857(US8835445, 41)
Affinity DataKi:  0.110nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131844(US8835445, 20)
Affinity DataKi:  0.120nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50448749(CHEMBL3127916 | US8835445, 15)
Affinity DataKi:  0.140nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131852(US8835445, 35)
Affinity DataKi:  0.160nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131856(US8835445, 39)
Affinity DataKi:  0.200nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131849(US8835445, 29)
Affinity DataKi:  0.400nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50351180(CHEMBL1818120 | US8835445, 7)
Affinity DataKi:  0.480nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131842(US8835445, 13)
Affinity DataKi:  0.5nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131839(US8835445, 10)
Affinity DataKi:  0.510nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50448748(CHEMBL3127917 | US8835445, 19)
Affinity DataKi:  0.600nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131838(US8835445, 9)
Affinity DataKi:  0.610nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131841(US8835445, 12)
Affinity DataKi:  0.650nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131837(US8835445, 8)
Affinity DataKi:  0.660nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131848(US8835445, 28)
Affinity DataKi:  0.720nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50351190(CHEMBL1818110 | US8835445, 5)
Affinity DataKi:  0.890nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131851(US8835445, 33)
Affinity DataKi:  0.910nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131840(US8835445, 11)
Affinity DataKi:  1.20nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131855(US8835445, 38)
Affinity DataKi:  1.40nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131843(US8835445, 14)
Affinity DataKi:  1.60nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131847(US8835445, 27)
Affinity DataKi:  2.60nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50351188(CHEMBL1818113 | US8835445, 1)
Affinity DataKi:  2.70nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50351191(CHEMBL1818109 | US8835445, 4)
Affinity DataKi:  2.70nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Trius Therapeutics

US Patent
LigandPNGBDBM50448745(CHEMBL3128013 | US8835445, 26)
Affinity DataKi:  2.90nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131836(US8835445, 3)
Affinity DataKi:  4nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM50351181(CHEMBL1818119 | US8835445, 6)
Affinity DataKi:  4.40nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Trius Therapeutics

US Patent
LigandPNGBDBM50351174(CHEMBL1818128 | US8835445, 31)
Affinity DataKi:  4.5nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Trius Therapeutics

US Patent
LigandPNGBDBM50351175(CHEMBL1818127 | US8835445, 30)
Affinity DataKi:  5.80nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Trius Therapeutics

US Patent
LigandPNGBDBM50448744(CHEMBL3128014 | US8835445, 25 | US8835445, 34)
Affinity DataKi:  7.60nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Trius Therapeutics

US Patent
LigandPNGBDBM50448744(CHEMBL3128014 | US8835445, 25 | US8835445, 34)
Affinity DataKi:  8.80nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131835(US8835445, 2)
Affinity DataKi:  15.3nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Trius Therapeutics

US Patent
LigandPNGBDBM50351180(CHEMBL1818120 | US8835445, 7)
Affinity DataKi:  26.3nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Trius Therapeutics

US Patent
LigandPNGBDBM131837(US8835445, 8)
Affinity DataKi:  27.5nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Trius Therapeutics

US Patent
LigandPNGBDBM50351173(CHEMBL1818129 | US8835445, 40)
Affinity DataKi:  34nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydrofolate reductase(Homo sapiens (Human))
Trius Therapeutics

US Patent
LigandPNGBDBM131841(US8835445, 12)
Affinity DataKi:  44nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In DepthDetails US Patent
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