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Found 9 Enz. Inhib. hit(s) with all data for entry = 6883
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM155924(US9018211, 5)
Affinity DataIC50:  7nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM155921(US9018211, 2A)
Affinity DataIC50:  9nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM155923(US9018211, 2C)
Affinity DataIC50:  10nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM155922(US9018211, 2B)
Affinity DataIC50:  12nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM155925(US9018211, 12)
Affinity DataIC50:  13nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM155926(US9018211, 20)
Affinity DataIC50:  14nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM155927(US9018211, 22 (isomer 2))
Affinity DataIC50:  15nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM155929(US9018211, 55)
Affinity DataIC50:  23nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM155928(US9018211, 52)
Affinity DataIC50:  36nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In DepthDetails US Patent