Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with all data for entry = 7425
TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM194087(US20230364079, Example Tirabrutinib | US9199997, 9...)
Affinity DataIC50:  375nMT: 2°CAssay Description:The measurement of Btk enzyme inhibitory activity was performed using the following reagents: Z'-LYTE Kinase Assay Kit-Tyr 1 (containing Tyr 1 peptid...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Fyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM194087(US20230364079, Example Tirabrutinib | US9199997, 9...)
Affinity DataIC50:  1.06E+3nMT: 2°CAssay Description:The measurement of Btk enzyme inhibitory activity was performed using the following reagents: Z'-LYTE Kinase Assay Kit-Tyr 1 (containing Tyr 1 peptid...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Lyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM194087(US20230364079, Example Tirabrutinib | US9199997, 9...)
Affinity DataIC50:  1.66E+3nMT: 2°CAssay Description:The measurement of Btk enzyme inhibitory activity was performed using the following reagents: Z'-LYTE Kinase Assay Kit-Tyr 1 (containing Tyr 1 peptid...More data for this Ligand-Target Pair
In DepthDetails US Patent