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Found 5 Enz. Inhib. hit(s) with all data for entry = 7511
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM98027(US10472367, Compound Formula I | US10919901, Compo...)
Affinity DataIC50:  0.550nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM98028(US10472367, Compound Formula II | US10919901, Comp...)
Affinity DataIC50:  0.550nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM98031(US10472367, Compound Formula V | US10919901, Compo...)
Affinity DataIC50:  0.550nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM98030(US10472367, Compound Formula IV | US10919901, Comp...)
Affinity DataIC50:  0.550nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte Holdings

US Patent
LigandPNGBDBM98029(US10472367, Compound Formula III | US10919901, Com...)
Affinity DataIC50:  0.550nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent