Compile Data Set for Download or QSAR
maximum 50k data
Found 54 Enz. Inhib. hit(s) with all data for entry = 7085
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50018008(CHEMBL3289671 | US9238653, Table 5, Compound 43)
Affinity DataIC50:  20nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50018006(CHEMBL3289672 | US9238653, Table 5, Compound 49)
Affinity DataIC50:  22nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365232(CHEMBL1956283 | US9238653, Table 5, Compound 54)
Affinity DataIC50:  28nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365230(CHEMBL1956285 | US9238653, Table 5, Compound 10)
Affinity DataIC50:  30nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345441(5-Methyl-N-(5,6,7,8-tetrahydronaphthalen-2yl)-[1,2...)
Affinity DataIC50:  32nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365225(CHEMBL1956290 | US9238653, Table 5, Compound 14)
Affinity DataIC50:  35nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50018007(CHEMBL3289670 | US9238653, Table 5, Compound 42)
Affinity DataIC50:  35nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365231(CHEMBL1738786 | US9238653, Table 5, Compound 7)
Affinity DataIC50:  38nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173505(US9238653, Table 5, Compound 44)
Affinity DataIC50:  42nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173492(US9238653, Table 5, Compound 15)
Affinity DataIC50:  43nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345406(CHEMBL1784574 | N-(4-tert-Butyl-3-fluorophenyl)-5-...)
Affinity DataIC50:  60nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365226(CHEMBL1956289 | US9238653, Table 5, Compound 52)
Affinity DataIC50:  75nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50396723(CHEMBL2172226 | US9238653, Table 5, Compound 2)
Affinity DataIC50:  77nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173488(US9238653, Table 5, Compound 4)
Affinity DataIC50:  90nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345385(CHEMBL1784580 | N-(Benzo[b]thiophen-5-yl)-5-methyl...)
Affinity DataIC50:  90nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365233(CHEMBL1956279 | US9238653, Table 5, Compound 53)
Affinity DataIC50:  93nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365241(CHEMBL1956269 | US9238653, Table 5, Compound 51)
Affinity DataIC50:  100nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345441(5-Methyl-N-(5,6,7,8-tetrahydronaphthalen-2yl)-[1,2...)
Affinity DataIC50:  100nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365242(CHEMBL1956268 | US9238653, Table 5, Compound 45)
Affinity DataIC50:  110nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173491(US9238653, Table 5, Compound 12)
Affinity DataIC50:  130nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365224(CHEMBL1956291 | US9238653, Table 5, Compound 29)
Affinity DataIC50:  130nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173497(US9238653, Table 5, Compound 21)
Affinity DataIC50:  130nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173495(US9238653, Table 5, Compound 18)
Affinity DataIC50:  140nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365234(CHEMBL1956278 | US9238653, Table 5, Compound 47)
Affinity DataIC50:  140nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365243(CHEMBL1956265 | US9238653, Table 5, Compound 50)
Affinity DataIC50:  150nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345414(CHEMBL1784567 | N-(4-Pentafluorosulfenylphenyl)-5-...)
Affinity DataIC50:  160nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345442(CHEMBL1784577 | N-(3,5-Difluoro-4-(trifluoromethyl...)
Affinity DataIC50:  190nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50365227(CHEMBL1956288 | US9238653, Table 5, Compound 46)
Affinity DataIC50:  190nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173496(US9238653, Table 5, Compound 19)
Affinity DataIC50:  200nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173489(US9238653, Table 5, Compound 5)
Affinity DataIC50:  220nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173490(US9238653, Table 5, Compound 6)
Affinity DataIC50:  250nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345388(5-Methyl-N-(1,2,3,4-tetrahydronaphthalen-2-yl)-[1,...)
Affinity DataIC50:  500nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173493(US9238653, Table 5, Compound 16)
Affinity DataIC50:  500nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345387(CHEMBL1784589 | N-(2,3-Dihydro-1H-inden-2-yl)-5-me...)
Affinity DataIC50:  500nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173502(US9238653, Table 5, Compound 35)
Affinity DataIC50:  510nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345405(CHEMBL1784575 | N-(4-Chloro-3-fluorophenyl)-5-meth...)
Affinity DataIC50:  510nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173503(US9238653, Table 5, Compound 36)
Affinity DataIC50:  520nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345404(CHEMBL1784576 | N-(3,4-Bis(trifluoromethyl)phenyl)...)
Affinity DataIC50:  540nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345415(5-Methyl-N-(4-(trifuoromethylthio)phenyl)-[1,2,4]t...)
Affinity DataIC50:  610nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345389(CHEMBL1784590 | N-(5-Fluoro-2,3-dihydro-1H-inden-2...)
Affinity DataIC50:  610nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345390(CHEMBL1784594 | N-(6-Fluoro-1,2,3,4-tetrahydronaph...)
Affinity DataIC50:  630nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345391(CHEMBL1784595 | N-(6-Choro-1,2,3,4-tetrahydronapht...)
Affinity DataIC50:  670nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173500(US9238653, Table 5, Compound 30)
Affinity DataIC50:  740nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345392(CHEMBL1784591 | N-(5-Bromo-2,3-dihydro-1H-inden-2-...)
Affinity DataIC50:  990nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173498(US9238653, Table 5, Compound 24)
Affinity DataIC50:  1.00E+3nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173504(US9238653, Table 5, Compound 41)
Affinity DataIC50:  1.20E+3nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM173494(US9238653, Table 5, Compound 17)
Affinity DataIC50:  1.20E+3nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345440(CHEMBL1784717 | N-(3-fluoro-4-methylphenyl)-6,7-di...)
Affinity DataIC50:  1.43E+3nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345437(6-ethyl-N-(4-isopropylphenyl)-5-methyl-[1,2,4]tria...)
Affinity DataIC50:  1.66E+3nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50345435(5-(Trifluoromethyl)-N-(4-trifluoromethyl)phenyl)-[...)
Affinity DataIC50:  1.70E+3nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In DepthDetails US Patent
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