Compile Data Set for Download or QSAR
maximum 50k data
Found 93 Enz. Inhib. hit(s) with all data for entry = 424
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268402(4-(3-(2,6-Dichlorobenzoyl)imidazo[1,5-a]pyridin-1-...)
Affinity DataEC50:  26nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268403(4-(6-(2,6-Dichlorobenzoyl)imidazo[1,5-a]pyrimidin-...)
Affinity DataEC50:  262nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268404(4-(3-(2-(Trifluoromethyl)benzoyl)imidazo[1,5-a]pyr...)
Affinity DataEC50:  8nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268405(4-(3-(2-(Trifluoromethyl)benzoyl)-5,6,7,8-tetrahyd...)
Affinity DataEC50:  1.00E+3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268406(1-(3-(2-chloro-6-(trifluoromethyl)benzoyl)imidazo[...)
Affinity DataEC50:  77nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268407(4-[3-[2- (trifluoromethyl)benzoyl]imidazo [1,5-a]p...)
Affinity DataEC50:  179nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268408(1-[3-[2- (trifluoromethyl)benzoyl]imidazo [1,5-a]p...)
Affinity DataEC50:  2.70E+3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268409(2-chloro-4-[3-[2- (trifluoromethyl)benzoyl]imidazo...)
Affinity DataEC50:  2.90E+3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268410(3-chloro-4-[3-[2- (trifluoromethyl)benzoyl]imidazo...)
Affinity DataEC50:  496nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268411(3-methyl-4-[3-[2- (trifluoromethyl)benzoyl]imidazo...)
Affinity DataEC50:  529nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268412(2-fluoro-4-[3-[2- (trifluoromethyl)benzoyl]imidazo...)
Affinity DataEC50:  486nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268413(2-hydroxy-4-[3-[2- (trifluoromethyl)benzoyl]imidaz...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268414(2-hydroxy-5-[3-[2- (trifluoromethyl)benzoyl]imidaz...)
Affinity DataEC50:  6.30E+3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268415(2,3-difluoro-4-[3-[2- (trifluoromethyl)benzoyl]imi...)
Affinity DataEC50:  358nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268416(3,5-difluoro-4-[3-[2- (trifluoromethyl)benzoyl]imi...)
Affinity DataEC50:  189nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268417(4-[3-(2,6- dichlorobenzoyl)imidazo[1,5 a]pyridin-1...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50106287(CHEMBL3598148 | US9550771, Example 17)
Affinity DataEC50:  2nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268419(4-[6-(2,6- dichlorobenzoyl)imidazo[1,5- a]pyrimidi...)
Affinity DataEC50:  84nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268420(4-[1-(2-fluoro-6-methoxy- benzoyl)-5,6,7,8- tetrah...)
Affinity DataEC50:  4.40E+3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268421(4-[3-[2- (trifluoromethyl)benzoyl]-5,6,7,8- tetrah...)
Affinity DataEC50:  2.20E+3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50106289(CHEMBL3596270 | US9550771, Example 21)
Affinity DataEC50:  32nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50106302(CHEMBL3598142 | US9550771, Example 22)
Affinity DataEC50:  58nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268424(4-[3-[2-chloro-6- (trifluoromethyl)benzoyl]-5,6,7,...)
Affinity DataEC50:  205nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268425(4-[3-[2-chloro-6- (trifluoromethyl)benzoyl]-5,6,7,...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268426(3-chloro-4-[3-[2-chloro-6- (trifluoromethyl)benzoy...)
Affinity DataEC50:  171nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268427(2-acetoxy-4-[3-[2-chloro-6- (trifluoromethyl)benzo...)
Affinity DataEC50:  7nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50106286(CHEMBL3598141 | US9550771, Example 27)
Affinity DataEC50:  10nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50106288(CHEMBL3598149 | US9550771, Example 28)
Affinity DataEC50:  9nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50106325(CHEMBL3598150 | US9550771, Example 29)
Affinity DataEC50:  103nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50106326(CHEMBL3598153 | US9550771, Example 30)
Affinity DataEC50:  539nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268432(4-[3-(2-chloro-6-prop-1-ynyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  202nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268433(4-[3-[2-chloro-6-(2- cyclopropylethynyl)benzoyl] i...)
Affinity DataEC50:  191nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268434(1-[3-[2-chloro-6- (trifluoromethyl)benzoyl]imidazo...)
Affinity DataEC50:  1.30E+3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268435(4-[3-(2-chloro-6-cyclopropyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  9nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268436(4-[3-(2-chloro-6-cyclopropyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  45nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268437(1-[3-(2-chloro-6-cyclopropyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  368nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268438(1-[3-[2-chloro-6- (trifluoromethyl)benzoyl]imidazo...)
Affinity DataEC50:  72nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268439(4-[3-(2- cyclopropylbenzoyl)imidazo[1,5- a]pyridin...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268440(6-[3-[2-chloro-6- (trifluoromethyl)benzoyl]imidazo...)
Affinity DataEC50:  111nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268441(4-[3-[2-chloro-6- (cyanomethyl)benzoyl]imidazo [1,...)
Affinity DataEC50:  195nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50106293(CHEMBL3596269 | US9550771, Example 41)
Affinity DataEC50:  97nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50106292(CHEMBL3598155 | US9550771, Example 92)
Affinity DataEC50:  437nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268444(4-[3-(2-chloro-6-cyclopropyl- benzoyl)-6- (dimethy...)
Affinity DataEC50:  6nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268445(4-[3-(2-chloro-6-cyclopropyl- benzoyl)-6- (dimethy...)
Affinity DataEC50:  22nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268446(1-[3-(2-chloro-6-cyclopropyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  139nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268447(4-[3-(2-chloro-6-cyclopropyl- benzoyl)imidazo[1,5-...)
Affinity DataEC50:  109nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268448(2-hydroxy-4-[3-(2- morpholinobenzoyl)imidazo[1,5- ...)
Affinity DataEC50:  50nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268449(4-[6-(azetidine-1-carbonyl)-3-(2- chloro-6-cyclopr...)
Affinity DataEC50:  3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268450((3S,4R)-1-[3-(2-chloro-6- cyclopropyl- benzoyl)imi...)
Affinity DataEC50:  63nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268451((3R,4R)-1-[3-(2-chloro-6- cyclopropyl- benzoyl)imi...)
Affinity DataEC50:  1.50E+3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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