Affinity Data by PDB ID

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

PDB code 1D4L

Identical Ligands in BindingDB

Found 6 hits Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Human immunodeficiency virus type 1 protease (89/99 = 90%)^† (Human immunodeficiency virus type 1)	BDBM50092151 ((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL DrugBank GoogleScholar	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibitory constant against HIV-1 protease				J Med Chem 43: 3495-504 (2000) Article DOI: 10.1021/jm000013n BindingDB Entry DOI: 10.7270/Q2KH0P1S
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Human immunodeficiency virus type 1 protease (89/99 = 90%)^† (Human immunodeficiency virus type 1)	BDBM50092151 ((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL DrugBank GoogleScholar	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Tested for inhibition of synthetic HIV-1 protease by using fluorometric assay				J Med Chem 47: 1641-51 (2004) Article DOI: 10.1021/jm030337m BindingDB Entry DOI: 10.7270/Q2JD4XJK
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Human immunodeficiency virus type 1 protease (89/99 = 90%)^† (Human immunodeficiency virus type 1)	BDBM50092151 ((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL DrugBank GoogleScholar	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of virion associated RT activity relative to untreated, infected control in PBMC cells infected with HIV-1 237288 strain				J Med Chem 43: 3495-504 (2000) Article DOI: 10.1021/jm000013n BindingDB Entry DOI: 10.7270/Q2KH0P1S
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Human immunodeficiency virus type 1 protease (89/99 = 90%)^† (Human immunodeficiency virus type 1)	BDBM50092151 ((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL DrugBank GoogleScholar	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of virion associated RT activity relative to untreated, infected control in MT2 cells infected with HIV-1 237288 strain				J Med Chem 43: 3495-504 (2000) Article DOI: 10.1021/jm000013n BindingDB Entry DOI: 10.7270/Q2KH0P1S
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Human immunodeficiency virus type 1 protease (89/99 = 90%)^† (Human immunodeficiency virus type 1)	BDBM50092151 ((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL DrugBank GoogleScholar	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of virion associated RT activity relative to untreated, infected control in cord blood mononuclear cells (CBMC) infected with HIV -1 TC354...				J Med Chem 43: 3495-504 (2000) Article DOI: 10.1021/jm000013n BindingDB Entry DOI: 10.7270/Q2KH0P1S
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Human immunodeficiency virus type 1 protease (89/99 = 90%)^† (Human immunodeficiency virus type 1)	BDBM50092151 ((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL DrugBank GoogleScholar	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of virion associated RT activity relative to untreated, infected control in MT2 cells infected with HIV-2 strain (ROD)				J Med Chem 43: 3495-504 (2000) Article DOI: 10.1021/jm000013n BindingDB Entry DOI: 10.7270/Q2KH0P1S
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

Reorder this table by ec50
Reorder this table by ic50
Reorder this table by Kd
Reorder this table by ki
Reorder this table by pH
Reorder this table by ΔG°
Reorder this table by ΔH°
Reorder this table by -TΔS°
Change energy units to: kcal/mole

Search BindingMOAD for More Affinity Data:

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output