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Found 4 Enz. Inhib. hit(s) for PDB: 1FVV
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7755(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50:  9.70nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7755(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50:  9.70nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM7755(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50:  10nMAssay Description:Inhibition of Cyclin-dependent kinase 2 cyclin AMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM7755(4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....)
Affinity DataIC50:  10nMAssay Description:Inhibition of Cyclin-dependent kinase 2More data for this Ligand-Target Pair