TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 0.0210nM ΔG°: -63.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,A572V](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: <0.0210nM ΔG°: <-63.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,D531N,A572V](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: <0.0210nM ΔG°: <-63.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 0.0210nM ΔG°: -63.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,M537I,A572V](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 0.0300nM ΔG°: -62.5kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0310nMAssay Description:Inhibition of HIV1 recombinant protease after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0350nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,L552P,A560V,V571A,L579M](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 0.0400nM ΔG°: -61.7kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A,D531N](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 0.0830nM ΔG°: -59.9kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,M537I](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 0.110nM ΔG°: -59.1kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,D531N,M537I](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 0.110nM ΔG°: -59.1kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,I543V,L552P,A560V,V571A,L579M](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 0.190nM ΔG°: -57.7kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,D531N,M537I,A572V](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 0.320nM ΔG°: -56.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
Affinity DataKi: 0.330nM ΔG°: -56.3kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,L552P,A560V,V571A,I573V,L579M](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 0.550nMAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,M535I,I543V,L552P,A560V,V571A,I573V,L579M](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 5.60nMAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,I543V,L552P,A560V,V571A,I573V,L579M](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 9.40nMAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 2.73E+3nMAssay Description:Inhibition of protease L10F/V32I/M46I/I47V/Q58E/I84V mutant in HIV1 A17 infected in human MT4 cells assessed as reduction in virus-induced cytopathic...More data for this Ligand-Target Pair