Found 5 Enz. Inhib. hit(s) for PDB: 1NO6 TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 2.40E+4nM ΔG°: -26.1kJ/mole Kd: 2.60E+4nMpH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
3D Structure (crystal)TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 3.90E+4nM ΔG°: -24.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Sunesis Pharmaceuticals
Curated by ChEMBL
Sunesis Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.90E+4nMAssay Description:Binding affinity for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Sunesis Pharmaceuticals
Curated by ChEMBL
Sunesis Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.58E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Sunesis Pharmaceuticals
Curated by ChEMBL
Sunesis Pharmaceuticals
Curated by ChEMBL
Affinity DataKd: 2.60E+4nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
