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Found 4 Enz. Inhib. hit(s) for PDB: 1O5A
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14142(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-phe...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14142(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-phe...)
Affinity DataKi:  33nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14142(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-phe...)
Affinity DataKi:  72nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
LigandPNGBDBM14142(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-phe...)
Affinity DataKi:  380nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair