Affinity Data by PDB ID

PDB code 1PYE

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
CDK2/CycE (298/298 = 100%)^† (Homo sapiens (Human))	BDBM6676 (3-benzoyl-6-[(2,6-difluorophenyl)carbonyl]imidazo[...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar	DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	25
Avenida de la Industria					Assay Description In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....				Bioorg Med Chem Lett 14: 6095-9 (2004) Article DOI: 10.1016/j.bmcl.2004.09.053 BindingDB Entry DOI: 10.7270/Q2ZP44BV
Avenida de la Industria					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output