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PDB code 2O65

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 2 hits Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-1

  (285/285 = 100%)
(Homo sapiens (Human))
BDBM26656
PNG
(5,7,3,4,5-pentahydroxyflavone | 5,7-dihydroxy-2-(3...)
Show SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1cc(O)c(O)c(O)c1
Show InChI InChI=1S/C15H10O7/c16-7-3-8(17)14-9(18)5-12(22-13(14)4-7)6-1-10(19)15(21)11(20)2-6/h1-5,16-17,19-21H
PDB
MMDB

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PDB
Article
PubMed
n/an/a 650n/an/an/an/a7.030



Loma Linda University



Assay Description
The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...


Mol Cancer Ther 6: 163-72 (2007)


Article DOI: 10.1158/1535-7163.MCT-06-0397
BindingDB Entry DOI: 10.7270/Q2N8783K
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Serine/threonine-protein kinase pim-1

  (285/285 = 100%)
(Homo sapiens (Human))
BDBM26656
PNG
(5,7,3,4,5-pentahydroxyflavone | 5,7-dihydroxy-2-(3...)
Show SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1cc(O)c(O)c(O)c1
Show InChI InChI=1S/C15H10O7/c16-7-3-8(17)14-9(18)5-12(22-13(14)4-7)6-1-10(19)15(21)11(20)2-6/h1-5,16-17,19-21H
PDB
MMDB

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KEGG

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UniProtKB/TrEMBL

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antibodypedia
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CHEBI
DrugBank
KEGG
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PC cid
PC sid
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UniChem

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PDB
Article
PubMed
n/an/a 646n/an/an/an/an/an/a



Loma Linda University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of PIM1 kinase


Bioorg Med Chem 15: 6463-73 (2007)

Checked by Author
Article DOI: 10.1016/j.bmc.2007.06.025
BindingDB Entry DOI: 10.7270/Q2C24W4S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output