Found 7 Enz. Inhib. hit(s) for PDB: 2V3D 
Affinity DataKi: 1.16E+5nM ΔG°: -23.4kJ/mole IC50: 2.70E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
3D Structure (crystal)TargetLysosomal acid/Non-lysosomal glucosylceramidase(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
Affinity DataIC50: 2.59E+5nMAssay Description:Inhibition of human placental beta-glucocerebrosidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of recombinant human GBA1More data for this Ligand-Target Pair
Affinity DataIC50: 3.99E+5nMAssay Description:Inhibition of human beta-glucocerebrosidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of GBA1 (unknown origin) using beta-D-[1-14C]glucocerebroside assessed as 4-methylumbelliferrone by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of recombinant GBA1 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
