Affinity DataKi: 2nMAssay Description:Binding affinity to human recombinant c-MET assessed as inhibition of autophosphorylation by continuous fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity to human recombinant c-MET assessed as inhibition of autophosphorylation by continuous fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Inhibition of recombinant MET using biotinylated-poly(GT) peptide as substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human GST-tagged c-MET using KKKSPGEYVNIEFG as substrate preincubated for 20 mins followed by [gamma-33P]ATP addition and measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of c-Met incubated for 60 mins at spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of c-Met kinase (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of purified recombinant c-MET (unknown origin) after 60 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human GST-tagged c-MET preincubated for 20 mins followed by [33P]-ATP addition measured after 2 hrs by Hot-SpotSM kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Compound was tested for H1-antihistamine activity in guinea pig ileum.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of C-Met (unknown origin) using polu (Glu,Tyr)4:1 substrate after 30 mins incubation by multi-well spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant c-MET kinase expressed in A549 cells assessed as inhibition of HGF-induced autophosphorylation by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of c-Met by cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of GST-tagged human c-MET preincubated for 20 mins followed by [33P]-ATP addition and measured after 2 hrs by Hot-Spot kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of c-Met kinase (unknown origin)More data for this Ligand-Target Pair
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology
Tianjin University Of Science And Technology
Affinity DataIC50: 13.7nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology
Tianjin University Of Science And Technology
Affinity DataIC50: 14.6nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human Met using FLPeptide 2 as substrate after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant c-MET kinase expressed in A549 cells assessed as inhibition of HGF-induced autophosphorylation by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of c-Met phosphorylation in human MKN845 cells after 1 hr by western blottingMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of c-Met phosphorylation in human MKN845 cells after 90 mins by Sandwich-ELISAMore data for this Ligand-Target Pair
Affinity DataKd: 2.10nMAssay Description:Binding constant for MET kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.550nMAssay Description:Binding constant for MET(M1250T) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Binding affinity to MET (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Binding constant for MET(Y1235D) kinase domainMore data for this Ligand-Target Pair