Found 9 Enz. Inhib. hit(s) for PDB: 3CD8 
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. Mole...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant c-Met kinase domain (unknown origin) incubated for 30 mins using gastrin peptide substrate by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of HGF-mediated human c-Met autophosphorylation expressed in human PC3 cells after 1 hr by electrochemiluminescent immunoassayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
China Pharmaceutical University
China Pharmaceutical University
Affinity DataIC50: 60nMAssay Description:The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem...More data for this Ligand-Target Pair
TargetALK tyrosine kinase/Hepatocyte growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University
China Pharmaceutical University
Affinity DataIC50: 80nMAssay Description:The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem...More data for this Ligand-Target Pair
TargetEpidermal/Hepatocyte growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University
China Pharmaceutical University
Affinity DataIC50: 90nMAssay Description:The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem...More data for this Ligand-Target Pair
