Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) for PDB: 3DOG
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Universite De Lyon

LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)
Affinity DataIC50:  40nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 15 uM ATP/ [gamma-33P]...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human recombinant CDK2/cyclinE using histone H1 and [gamma-33P]ATP incubated fro 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Universite De Lyon

LigandPNGBDBM27217((2R)-2-{[4-(benzylamino)-8-(propan-2-yl)pyrazolo[1...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human recombinant CDK2/cyclin A using histone H1 and [gamma-33P]ATP incubated fro 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair