TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Inhibition of wild-type HIV1 BH10 protease expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.931nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Curated by ChEMBL
Agouron Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant wild type HIV1 protease assessed as hydrolysis of fluorogenic substrateMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of wild type HIV-1 protease assessed as hydrolysis of fluorogenic substrate Abz-Thr-Ile-Nle-Phe(NO2)-Gln-Arg after 10 mins by fluorescence...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Curated by ChEMBL
Agouron Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Compound was tested for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKd: 3nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 5.1More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKd: 38nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 4.1More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataKd: 3.40nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 7.4More data for this Ligand-Target Pair