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Report error Found 2 Enz. Inhib. hit(s) for PDB: 3FV8

Mitogen-activated protein kinase 8(Human)
The Scripps Research Institute

BDBM32460(piperazine amide, 4g)

IC50: 140nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

DrugBank PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Isoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Human)
The Scripps Research Institute

BDBM32460(piperazine amide, 4g)

IC50: 160nMpH: 7.0 T: 22°CAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar

DrugBank PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)