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Found 2 Enz. Inhib. hit(s) for PDB: 3IXK
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312538(CHEMBL1076902 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of BACE1 after 30 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312538(CHEMBL1076902 | N-[(1S,2S,4R)-4-((S)-1-Benzylcarba...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human BACE1 in HEK293 cells stably co-transfected with mutant APP(swAPP751) assessed as Amyloid beta 1-40 level after 24 hrs by ELISAMore data for this Ligand-Target Pair