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Found 3 Enz. Inhib. hit(s) for PDB: 3K2P
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences

LigandPNGBDBM33411(β-Thujaplicinol | hydroxytropolone, 3)
Affinity DataIC50:  660nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences

LigandPNGBDBM33411(β-Thujaplicinol | hydroxytropolone, 3)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of HIV-1 BH10 reverse transcriptase RNase H activity expressed in Escherichia coli using [32P]-labeled template primer 31Trna/21P as subst...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Mcgill University

LigandPNGBDBM33411(β-Thujaplicinol | hydroxytropolone, 3)
Affinity DataIC50:  3.80E+3nMpH: 7.8 T: 2°CAssay Description:To compare activity and inhibition of E. coli RNase H with HIV-1 RNase H, theconcentration of the E. coli was adjusted to the efficiency of 500 nM HI...More data for this Ligand-Target Pair