BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) for PDB: 3KAI

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM50305682((2R)-2-[(2-methyl-5-phenyl-pyrazol-3-yl)carbonylam...)

IC50: 3.90E+3nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL MMDB PC cid PC sid PDB

Details Article PubMed MMDB
PDB

3D Structure (crystal)

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM50133487(CHEMBL3633019)

IC50: 4.20E+3nMAssay Description:Inhibition of Pin-1 (unknown origin) using suc-Ala-Glu-Pro-Phe-pNA as substrate preincubated for 10 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)