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Found 5 Enz. Inhib. hit(s) for PDB: 3Q92
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50380246(CHEMBL2017214)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50380246(CHEMBL2017214)
Affinity DataIC50:  12nMAssay Description:Inhibition of human ketohexokinase isoform C expressed in Escherichia coli BL21 (DE3) cells using D-fructose as substrate after 12 to 15 mins by fluo...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50380246(CHEMBL2017214)
Affinity DataIC50:  12nMAssay Description:Inhibition of KHK (unknown origin) using D-fructose as substrate after 60 mins in presence of ATP by LC-MS analysisMore data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50380246(CHEMBL2017214)
Affinity DataIC50:  400nMAssay Description:Inhibition of human ketohexokinase isoform C expressed in Escherichia coli BL21 (DE3) cells using D-fructose as substrate after 12 to 15 mins by fluo...More data for this Ligand-Target Pair
TargetKetohexokinase(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50380246(CHEMBL2017214)
Affinity DataIC50: <500nMAssay Description:Inhibition of recombinant human hepatic KHKCMore data for this Ligand-Target Pair