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Report error Found 4 Enz. Inhib. hit(s) for PDB: 3SMQ
TargetProtein arginine N-methyltransferase 3 [N508S](Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50427768(CHEMBL2325441)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant human PRMT3 (211 to 531) using histone-4 (1 to 24) as substrate by S-adenosylhomocysteine hydrolase-coupled assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3 [N508S](Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50427768(CHEMBL2325441)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50427768(CHEMBL2325441)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of full length PRMT3 (unknown origin) using biotinylated histone H4 as substrate after 60 mins in presence of [3H]S-adenosylmethionine by ...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3 [N508S](Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50427768(CHEMBL2325441)
Affinity DataKd:  9.50E+3nMAssay Description:Binding affinity to 6xHis-tagged recombinant human PRMT3 by surface plasmon resonance analysisMore data for this Ligand-Target Pair