Found 5 Enz. Inhib. hit(s) for PDB: 3UEL TargetPoly(ADP-ribose) glycohydrolase(Rattus norvegicus)
Kumamoto Health Science University
Curated by ChEMBL
Kumamoto Health Science University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 120nMAssay Description:Inhibition of PARG using [alpha-32P]ADP-ribose polymers after 5 mins by TRAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:The compound was tested for its ability to inhibit bovine thymus polyadenosine diphosphoribose glycohydrolase (bPARG)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was tested for its ability to inhibit recombinant bovine polyadenosine diphosphoribose glycohydrolase catalytic fragment (rPARG-CF)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:The compound was tested for its ability to inhibit recombinant bovine polyadenosine diphosphoribose glycohydrolase catalytic fragment (rPARG-CF)More data for this Ligand-Target Pair
