Affinity Data by PDB ID

PDB code 4AW0

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 (308/310 > 99%)^† (Homo sapiens (Human))	BDBM104018 (PS182) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	7.4	0
Universit£tsklinikum Frankfurt					Assay Description The AlphaScreen Assay (Perkin Elmer) was performed according to the manufacturer's protocol in 384-well microtiter plates. Incubations were performe...				ACS Chem Biol 8: 2283-92 (2013) Article DOI: 10.1021/cb400452z BindingDB Entry DOI: 10.7270/Q2N878F2
Universit£tsklinikum Frankfurt					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output