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Found 6 Enz. Inhib. hit(s) for PDB: 4D4S
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FAK cytoplasmic domain (393 to 698 residues) expressed in baculovirus infected sf9 cells assess...More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  7nMAssay Description:Inhibition of FAK (unknown origin) using Ulight-poly(Glu:Tyr)(4:1) as substrate after 1.6 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  7nMAssay Description:Inhibition of FAK (unknown origin) using ULight-poly GT as substrate after 1.6 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50:  7nMAssay Description:Inhibition of pre-activated recombinant full length FAK (unknown origin) using ULight labeled poly(Glu/Tyr) as substrate after 1.6 hrs by TR-FRET ass...More data for this Ligand-Target Pair