Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) for PDB: 4Y73
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50095474(CHEMBL3590478 | US10329294, Example 2)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human IRAK4 assessed as phosphorylation of fluorescent peptide substrate after 30 mins by fluorescent polarization readerMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50095474(CHEMBL3590478 | US10329294, Example 2)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50095474(CHEMBL3590478 | US10329294, Example 2)
Affinity DataIC50:  0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50095474(CHEMBL3590478 | US10329294, Example 2)
Affinity DataIC50:  9nMAssay Description:Inhibition of IRAK4 in human PBMCMore data for this Ligand-Target Pair