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Found 3 Enz. Inhib. hit(s) for PDB: 4YFI
TargetSerine/threonine-protein kinase TNNI3K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118389(CHEMBL3612641)
Affinity DataIC50:  500nMAssay Description:Displacement of 5-({[2-({[3-({4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl}amino)phenyl]carbonyl}amino)-ethyl]amino}carbonyl)-2-(6-hydroxy-3-oxo...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TNNI3K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118389(CHEMBL3612641)
Affinity DataIC50:  500nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase TNNI3K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50118389(CHEMBL3612641)
Affinity DataKd:  111nMAssay Description:Binding affinity to TNNI3K (unknown origin)More data for this Ligand-Target Pair