TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human Keap1 kelch domain binding to Nrf2-ETGE peptide preincubated for 15 mins followed by peptide addition measured after 30 mins by f...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human Keap1 kelch domain (Ala321 to Thr609 residues) binding to fluorescent labeled Nrf2 peptide preincubated for 15 mins followed by N...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKd: 6.00E+3nMAssay Description:Inhibition of human Keap1 kelch domain binding to Nrf2-ETGE peptide by ITC assayMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Mus musculus)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKd: 6.00E+3nMAssay Description:Binding affinity to mouse Keap1 Kelch domain expressed in Escherichia coli BL21 by VP-ITC assayMore data for this Ligand-Target Pair