Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) for PDB: 5CGJ
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50200467(CHEMBL3899754)
Affinity DataIC50:  140nMAssay Description:Inhibition of human Keap1 kelch domain binding to Nrf2-ETGE peptide preincubated for 15 mins followed by peptide addition measured after 30 mins by f...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50190618(CHEMBL3827019)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Keap1 kelch domain (Ala321 to Thr609 residues) binding to fluorescent labeled Nrf2 peptide preincubated for 15 mins followed by N...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50200467(CHEMBL3899754)
Affinity DataKd:  6.00E+3nMAssay Description:Inhibition of human Keap1 kelch domain binding to Nrf2-ETGE peptide by ITC assayMore data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Mus musculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200467(CHEMBL3899754)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity to mouse Keap1 Kelch domain expressed in Escherichia coli BL21 by VP-ITC assayMore data for this Ligand-Target Pair