Found 3 Enz. Inhib. hit(s) for PDB: 5CSX TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Albert Einstein College Of Medicine
Curated by ChEMBL
Albert Einstein College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) by Z'-LYTE assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Albert Einstein College Of Medicine
Curated by ChEMBL
Albert Einstein College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BRAF V600E mutant in human A375 cells assessed as reduction in ERK phosphorylation after 2 hrs by ELISAMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Albert Einstein College Of Medicine
Curated by ChEMBL
Albert Einstein College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of wild type BRAF (unknown origin) by Z'-LYTE assayMore data for this Ligand-Target Pair
