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Found 3 Enz. Inhib. hit(s) for PDB: 5EGS
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataIC50:  230nMAssay Description:Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of FLAG-tagged human PRMT6 expressed in HEK293 cells assessed as reduction in H3R2 global methylation incubated for 20 hrs by Western blot...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50158094(CHEMBL3780926)
Affinity DataKd:  970nMAssay Description:Binding affinity to Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells by ITC methodMore data for this Ligand-Target Pair