Found 6 Enz. Inhib. hit(s) for PDB: 5J9Y TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University
Curated by ChEMBL
Wenzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of N-terminal GST-fused human EGFR cytoplasmic domain T790M/C797S mutant expressed in baculovirus expression system using TK-substrate aft...More data for this Ligand-Target Pair
3D Structure (crystal)TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University
Curated by ChEMBL
Wenzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R/T790M double mutant expressed in baculovirus expression system preincubated for 30 mins followe...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University
Curated by ChEMBL
Wenzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of wild type N-terminal GST-fused human EGFR cytoplasmic domain expressed in baculovirus expression system using TK-substrate after 25 min...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University
Curated by ChEMBL
Wenzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of wild type N-terminal GST-fused human EGFR cytoplasmic domain expressed in baculovirus expression system preincubated for 30 mins follow...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University
Curated by ChEMBL
Wenzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of wild type N-terminal GST-fused human EGFR cytoplasmic domain expressed in baculovirus expression system preincubated for 30 mins follow...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wenzhou Medical University
Curated by ChEMBL
Wenzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of recombinant human EGFR L858R/T790M/C797S mutant using TK-substrate after 10 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
