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Found 4 Enz. Inhib. hit(s) for PDB: 5N7V
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50386816(CHEMBL2047943)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of GST-fused full length human TTK compound pre-incubated for 15 mins prior ATP addition by MBP-based assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50386816(CHEMBL2047943)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human MPS1 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50386816(CHEMBL2047943)
Affinity DataIC50:  4nMAssay Description:Inhibition of Mps1More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50386816(CHEMBL2047943)
Affinity DataIC50:  5nMAssay Description:Inhibition of full-length Mps1 kinase (unknown origin)More data for this Ligand-Target Pair