Affinity DataKi: 0.927nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 106nMAssay Description:Displacement of [3H]-LY459477 from mGlu2/3 receptor in Sprague-Dawley rat forebrain primary cortical membranes after 90 mins by liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing rat EAAT1/Galpha15 assessed as induction of increa...More data for this Ligand-Target Pair
Affinity DataEC50: 0.470nMAssay Description:Agonist activity at human mGlu3 receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP formation after 20 mins by HTRF a...More data for this Ligand-Target Pair